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Award Abstract #0103105
NER: Porous Scaffolds Using Dendrimer Templated Bioceramic Nanopowders

| NSF Org: |
CBET
Division of Chemical, Bioengineering, Environmental, and Transport Systems
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| Initial Amendment Date: |
July 17, 2001 |
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| Latest Amendment Date: |
July 17, 2001 |
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| Award Number: |
0103105 |
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| Award Instrument: |
Standard Grant |
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| Program Manager: |
Cyrus K. Aidun
CBET Division of Chemical, Bioengineering, Environmental, and Transport Systems
ENG Directorate for Engineering
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| Start Date: |
July 15, 2001 |
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| Expires: |
June 30, 2002 (Estimated) |
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| Awarded Amount to Date: |
$99685 |
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| Investigator(s): |
Susmita Bose sbose@wsu.edu (Principal Investigator)
Howard Hosick (Co-Principal Investigator) Amit Bandyopadhyay (Co-Principal Investigator)
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| Sponsor: |
Washington State University
NEILL HALL, ROOM 423
PULLMAN, WA 99164 509/335-9661
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| NSF Program(s): |
MATERIALS AND SURFACE ENG, PARTICULATE &MULTIPHASE PROCES
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| Field Application(s): |
0308000 Industrial Technology
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| Program Reference Code(s): |
OTHR, 1676, 0000
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| Program Element Code(s): |
1633, 1415
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ABSTRACT

Abstract
CTS-0103105
Susmita Bose, Et. Al, Washington State University
This project will investigate the synthesis route for making nano-powders of calcium phosphate based ceramics. It will explore the possibility of dendrimer mediated synthesis of nano-powders of calcium phosphate based ceramics that can be used for making dense and porous bone grafts with improved mechanical properties. Among various ceramic materials, calcium phosphate based ceramics are of significant interest because of their excellent biocompatibility. However, the composition suffer from poor mechanical properties due to sintering. The sinterability issues of these and other calcium phosphate based compositions will be evaluated using nano-sized powders. It is believed that the higher surface area of the starting nano-powders will increase the sintering kinetics, and better sintering will improve mechanical properties. The nano-powders will be synthesized by using different dendrimers via sol-gel synthetic route. Preliminary cell proliferation tests will also be conducted with these bone grafts.
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