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Award Abstract #0103447
Protein Logic

| NSF Org: |
CHE
Division of Chemistry
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| Initial Amendment Date: |
September 6, 2001 |
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| Latest Amendment Date: |
September 1, 2005 |
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| Award Number: |
0103447 |
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| Award Instrument: |
Standard Grant |
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| Program Manager: |
Katharine J. Covert
CHE Division of Chemistry
MPS Directorate for Mathematical & Physical Sciences
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| Start Date: |
September 1, 2001 |
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| Expires: |
August 31, 2006 (Estimated) |
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| Awarded Amount to Date: |
$1150000 |
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| Investigator(s): |
Joseph Lyding j-lyding@casper.beckman.uiuc.edu (Principal Investigator)
Jeffrey Moore (Co-Principal Investigator) Stephen Sligar (Co-Principal Investigator) Paul Braun (Co-Principal Investigator) Gregory Timp (Co-Principal Investigator)
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| Sponsor: |
University of Illinois at Urbana-Champaign
SUITE A
CHAMPAIGN, IL 61820 217/333-2187
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| NSF Program(s): |
SPECIAL PROJECTS - CCF, QuBIC, NANOSCALE: INTRDISCPL RESRCH T, PARTICULATE &MULTIPHASE PROCES
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| Field Application(s): |
0106000 Materials Research
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| Program Reference Code(s): |
AMPP, 9179, 9162, 9107, 1674
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| Program Element Code(s): |
2878, 1708, 1674, 1415
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ABSTRACT

Divisions of Chemistry, Molecular and Cellular Biosciences, Chemical Transport Systems, Computer-Communications Research, and Experimental and Integrated Activities support this multidivisional award to University of Illinois Urbana-Champaign. This Nanoscale Interdisciplinary Research Team (NIRT) award is part of the Nanoscale Science and Engineering program. Under this project, an interdisciplinary team with Joseph Lyding as the principal investigator will develop protein-based logic chips that interfaces between biochemical reactions and conventional microfabricated silicon-based electronics such as metal-oxide semiconductor (MOSFETs) taking advantage of biocomplexity and electronic speed. These protein interfaced MOSFETs will help to create atomically accurate protein arrays to function as cellular nonlinear/neural network, and this in turn will help to over come the 100 nm limit in miniaturization of the present transistor technology. Industrial collaborations and outreach programs in the K-12 system will be part of the project.
Under the award, ordered and atomically accurate protein arrays that interfaces between biochemical reactions and conventional microfabricated silicon-based electronics will be developed. Strong industrial collaboration will help in the industrial development and technology transfer of this science. In addition, the research program will provide multidisciplinary education and training opportunities in materials chemistry, protein chemistry and electronics to students from K-12 to post doctoral candidates.
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