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Award Abstract #0128052
SBIR/STTR PHASE I: Fluorescent Polymeric Nanoparticles
| NSF Org: |
IIP
Division of Industrial Innovation and Partnerships
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| Initial Amendment Date: |
November 8, 2001 |
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| Latest Amendment Date: |
November 8, 2001 |
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| Award Number: |
0128052 |
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| Award Instrument: |
Standard Grant |
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| Program Manager: |
Cheryl F. Albus
IIP Division of Industrial Innovation and Partnerships
ENG Directorate for Engineering
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| Start Date: |
January 1, 2002 |
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| Expires: |
June 30, 2002 (Estimated) |
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| Awarded Amount to Date: |
$99999 |
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| Investigator(s): |
Lawrence Hancock lhancock@nomadics.com (Principal Investigator)
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| Sponsor: |
NOMADICS, INC
1024 S INNOVATION WAY
STILLWATER, OK 74074 405/372-9535
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| NSF Program(s): |
SMALL BUSINESS PHASE I
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| Field Application(s): |
0308000 Industrial Technology
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| Program Reference Code(s): |
MANU, 9146, 1788
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| Program Element Code(s): |
5371
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ABSTRACT
This Small Business Innovation Research Phase I project will exploit the unique fluorescence and signal amplification qualities of poly(phenylene ethynylene)s in a nanoparticle format. This combines the intense solid-state fluorescence and sensing capabilities of poly(phenylene ethynylene)s (PPEs) with the many unique attributes of nanoparticles, including their tremendous surface area and their surface adsorptivity. In this project, a series of charged PPEs whose emissions span the color spectrum will be synthesized and systematically evaluated for the formation of stable, aqueous nanoparticle dispersions. They will be functionalized and conjugated to biologic recognition molecules (i.e. antibodies and nucleic acids). The Phase I effort will yield a series of functional, highly fluorescent nanoparticles which may be used directly for the labeling of biological molecules.
The commercial applications of this project will be in standoff explosives detection for wide area mapping. Standoff, wide area mapping is of intense interest for military and humanitarian uses as well as for environmental remediation of explosives contamination.
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