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Award Abstract #0215819
SBIR Phase II: Nanomaterial for Microchip Chemical Sensors

| NSF Org: |
IIP
Division of Industrial Innovation and Partnerships
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| Initial Amendment Date: |
September 9, 2002 |
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| Latest Amendment Date: |
July 12, 2004 |
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| Award Number: |
0215819 |
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| Award Instrument: |
Standard Grant |
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| Program Manager: |
T. James Rudd
IIP Division of Industrial Innovation and Partnerships
ENG Directorate for Engineering
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| Start Date: |
September 15, 2002 |
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| Expires: |
February 28, 2005 (Estimated) |
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| Awarded Amount to Date: |
$514925 |
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| Investigator(s): |
Stuart Farquharson stu@rta.biz (Principal Investigator)
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| Sponsor: |
REAL-TIME ANALYZERS, INCORPORATED
362 INDUSTRIAL PARK RD #8
MIDDLETOWN, CT 06457 860/635-9800
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| NSF Program(s): |
SMALL BUSINESS PHASE II
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| Field Application(s): |
0308000 Industrial Technology
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| Program Reference Code(s): |
AMPP, 9251, 9178, 9163, 1415
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| Program Element Code(s): |
5373
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ABSTRACT

This Small Business Innovation Research (SBIR) Phase II Project will develop a novel microchip chemical analyzer that incorporates a new nanomaterial that performs both separation and detection of small quantities of chemicals and biochemicals. Phase I demonstrated feasibility by incorporating a proprietary nanomaterial in 20- by 50-micron channels etched in a glass microchip and performing chemical separation and surface-enhanced Raman spectral analysis of several test chemicals. Phase II will complete development of the microchip chemical analyzer by designing reproducible plastic microchip cards that fit into an integrated micro-fluidics and Raman system. Development will include the following chemicals: p-aminobenzoic acid, phenyl acetylene, adenine, acetaminophen, secobarbitol, cocaine, and related metabolites.
The microchip analyzer will have broad commercial value to the agricultural, biotech, chemical agents, environmental, medical and pharmaceutical industries. Specifically, the microchip is being designed to measure drugs and metabolites in body fluids to aid clinical trials of new drugs, assist dosage control of chemotherapeutic drugs, and diagnose drug overdose.
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