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Award Abstract #0225805
SGER: Bioengineering a SPM Based Nanomanipulator With Landmark Referenced Control
| NSF Org: |
CBET
Division of Chemical, Bioengineering, Environmental, and Transport Systems
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| Initial Amendment Date: |
August 28, 2002 |
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| Latest Amendment Date: |
August 28, 2002 |
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| Award Number: |
0225805 |
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| Award Instrument: |
Standard Grant |
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| Program Manager: |
Semahat S. Demir
CBET Division of Chemical, Bioengineering, Environmental, and Transport Systems
ENG Directorate for Engineering
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| Start Date: |
September 1, 2002 |
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| Expires: |
August 31, 2004 (Estimated) |
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| Awarded Amount to Date: |
$46628 |
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| Investigator(s): |
Virginia Ayres ayresv@egr.msu.edu (Principal Investigator)
Fathi Salem (Co-Principal Investigator)
Ning Xi (Co-Principal Investigator)
Donna Wang (Co-Principal Investigator)
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| Sponsor: |
Michigan State University
CONTRACT AND GRANT ADMINISTRATIO
EAST LANSING, MI 48824 517/355-5040
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| NSF Program(s): |
BIOMEDICAL ENGINEERING,
NANOMANUFACTURING,
PHYSICS-OTHER
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| Field Application(s): |
0203000 Health
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| Program Reference Code(s): |
OTHR, MANU, 9237, 9146, 0000
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| Program Element Code(s): |
5345, 1788, 1248
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ABSTRACT
0228508
Ayres
The goal of the proposed work is to combine high-resolution Scanning Probe Microscope (SPM)-based imaging that has been achieved for biological specimens with a novel approach to SPM-based nanomanipulation to yield a significant new approach for direct nanobiological investigations. To achieve efficient and reliable manipulation in a micro/nano environment, capabilities of sensing, processing and actuation in dynamic interactions are essential. Using the proposed approach, signals that would normally be projected as an SPM image are acquired and essential information is extracted for subsequent use as the sensing component within a feedback control loop formulation. The control loop is used to accurately steer the probe's tip along a prescribed trajectory. The feedback loop formulation involves landmark recognition and dynamic pattern matching through adaptive learning. With this capability, the tip is able to return to and stay centered on a specific site by recognizing the way the site feels to the probe tip. Except for high-level commands, the human operator can be eliminated from the operation and the full potential of this instrument with inherently sub-nanometer resolution can be utilized.
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