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Award Abstract #0423557
Biophotonics: MEMS-Based Endoscopic Optical Confocal Imaging
| NSF Org: |
CBET
Division of Chemical, Bioengineering, Environmental, and Transport Systems
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| Initial Amendment Date: |
September 2, 2004 |
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| Latest Amendment Date: |
September 2, 2004 |
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| Award Number: |
0423557 |
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| Award Instrument: |
Standard Grant |
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| Program Manager: |
Leon Esterowitz
CBET Division of Chemical, Bioengineering, Environmental, and Transport Systems
ENG Directorate for Engineering
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| Start Date: |
September 1, 2004 |
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| Expires: |
August 31, 2008 (Estimated) |
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| Awarded Amount to Date: |
$450000 |
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| Investigator(s): |
Huikai Xie hkxie@ece.ufl.edu (Principal Investigator)
Toshikazu Nishida (Co-Principal Investigator)
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| Sponsor: |
University of Florida
1 UNIVERSITY OF FLORIDA
GAINESVILLE, FL 32611 352/392-3516
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| NSF Program(s): |
BIOPHOTONICS, IMAGING &SENSING
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| Field Application(s): |
0000099 Other Applications NEC
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| Program Reference Code(s): |
OTHR, 0000
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| Program Element Code(s): |
7236
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ABSTRACT
0423557
Xie
In this project, a new MEMS-based OCM (u-OCM) imaging system is proposed. The proposed imaging probe will be only 5 mm in diameter. The fast scanning (< 1 millisecond) and large z-axis tunable range (~2 mm) of the employed microlens is enabled by a novel large-vertical-displacement (LVD) microactuator technique. The following tasks will be pursued: 1) to develop LVD microactuators with at least 2-mm z-axis travel range; 2) to design and fabricate LVD micromirrors and microlenses; 3) to package and assemble LVD micromirrors and microlenses into a fiberoptic imaging probe; and 4) to test the imaging probe in physical phantoms.
PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH
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(Showing: 1 - 10 of 24)
(Showing: 1 - 24 of 24)
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A. Jain and H. Xie. "Half-Millimeter-Range Vertically Scanning Microlenses for Microscopic Focusing Applications," Hilton Head 2006: Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head Island, SC, June 2006., 2006, p. 74.
A. Jain and H. Xie. "Microendoscopic Confocal imaging probe based on a LVD microlens scanner," IEEE Journal of Selected Topics in Quantum Electronics, v.13, 2007, p. 228.
A. Jain, H. Qu, S. Todd, and H. Xie. "A Thermal Bimorph Micromirror with Large Bi-Directional and Vertical Actuation," Sensors & Actuators, v.122, 2005, p. 9.
Ankur Jain, Huikai Xie. "Endoscopic Microprobe with a LVD Microlens Scanner for Confocal Imaging," The 2006 IEEE/LEOS International Conference on Optical MEMS and Their Applications, 21 - 24 August 2006, Big Sky, Montana, USA, 2006, p. 168.
Fu, L., Jain, A., Xie, H., Cranfield, C., and Gu, M.,. "Nonlinear Optical Endoscopy based on a Double-clad Photonic Crystal Fiber and a MEMS Mirror," Optics Express, v.14, 2006, p. 1027.
H. Xie. "MEMS-Based Optical Coherence Imaging," the International Conference on Quantum Electronics 2005 and the Pacific Rim Conference on Lasers and Electro-Optics 2005 (IQEC/CLEO-PR 2005), July 11-15, Tokyo, Japan, 2005, p. 187.
H. Xie, G. K. Fedder and Y. Pan. "MEMS-based Optical Coherence Tomography," Proceedings of at the SPIE Photonics West: MOEMS-MEMS 2005, 22-27 January 2005, San Jose, CA, USA, v.5721, 2005, p. 33.
Huikai Xie. "MEMS-based endoscopic optical coherence tomography," The 3rd Asian and Pacific Rim Symposium on Biophotonics, 2007.
Jain, A., and Xie, H.. "An Electrothermal Microlens Scanner with Low-Voltage, Large-Vertical-Displacement Actuation," IEEE Photonics Technology Letters., v.17, 2005, p. 1971.
Jain, A., and Xie, H.. "A Single-Crystal-Silicon Micromirror for Large Bi-directional 2-D Scanning Applications," Sensors and Actuators A, v.130-131, 2006, p. 454.
Jain, A., and Xie, H.. "A Tunable Microlens Scanner with Large-Vertical-Displacement Actuation," The 18th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2005), v.18, 2005, p. 92.
Jain, A., and Xie, H.. "An Electrothermal SCS Micromirror for Large Bi-Directional 2-D Scanning," The 13th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2005), v.13, 2005, p. 988.
L. Wu and H. Xie. "A Lateral-Shift-Free and Large-Vertical-Displacement Electrothermal Actuator for Scanning Micromirror/Lens," Proceedings of Transducers 2007, 2007.
L. Wu and H. Xie. "A Lateral-Shift-Free and Large-Vertical-Displacement Electrothermal Actuator for Scanning Micromirror/Lens," Proceedings of Transducers 2007, 2007, p. 1075.
L. Wu and H. Xie. "A 124° rotation angle electrothermal micromirror with integrated platinum heater," IEEE Journal of Selected Topics in Quantum Electronics, v.13, 2007, p. 316.
Lei Wu, and Huikai Xie. "A Large Rotation Angle Electrothermal Micromirror with Integrated Platinum Heater," The 2006 IEEE/LEOS International Conference on Optical MEMS and Their Applications, 21 - 24 August 2006, Big Sky, Montana, USA, 2006, p. 106.
Lei Wu, Huikai Xie. "A large vertical displacement electrothermal bimorph microactuator with very small lateral shift," Sensors & Actuators A, v.145, 2008, p. 371.
Ling Fu, Ankur Jain, Charles Cranfield, Huikai Xie, and Min Gu. "Three-dimensional nonlinear optical endoscopy," Journal of Biomedical Optics, v.12, 2007, p. 040501.
Ling Fu, Ankur Jain, Charles Cranfield, Huikai Xie, and Min Gu. "Three-dimensional nonlinear optical endoscopy," Journal of Biomedical Optics, v.12, 2007, p. 40501.
S. Todd, A. Jain, H. Qu, and H. Xie. "A 3-D Micromirror Utilizing Inverted-Series-Connected Electrothermal Bimorph Actuators for Piston and Tilt Motion," the IEEE/LEOS International Conference on Optical MEMS and Their Applications, 1-4 August 2005, Oulu, Finland, 2005, p. 121.
Shane T. Todd, Huikai Xie. "An Electrothermomechanical Lumped Element Model of an Electrothermal Bimorph Actuator," Journal of Microelectromechanical Systems, v.17, 2008, p. 213.
Todd, S. T., Jain, A., Qu, H., and Xie, H.. "A Multi-Degree-of-Freedom Micromirror Utilizing Inverted-Series-Connected Bimorph Actuators," Journal of Optics A: Pure and Applied Optics, v.8, 2006, p. 352.
Z. Wang, C. Lee, W.C. Waltzer, J. Liu, H. Xie, Z. Yuan, and Y. Pan. "in vivo bladder imaging with MEMS-based endoscopic Spectral Domain Optical Coherence Tomography," Journal of Biomedical Optics, v.12, 2007, p. 034009.
Z. Wang, C. Lee, W.C. Waltzer, J. Liu, H. Xie, Z. Yuan, and Y. Pan. "in vivo bladder imaging with MEMS-based endoscopic Spectral Domain Optical Coherence Tomography," Journal of Biomedical Optics, v.12, 2007, p. 34009.
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