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Award Abstract #0427374
ITR: (ASE)-(sim+dmc+int): Computational Simulation, Modeling, and Visualization for Understanding Unsteady Bioflows

| NSF Org: |
CNS
Division of Computer and Network Systems
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| Initial Amendment Date: |
September 16, 2004 |
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| Latest Amendment Date: |
August 21, 2007 |
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| Award Number: |
0427374 |
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| Award Instrument: |
Continuing grant |
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| Program Manager: |
D. Helen Gill
CNS Division of Computer and Network Systems
CSE Directorate for Computer & Information Science & Engineering
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| Start Date: |
October 1, 2004 |
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| Expires: |
September 30, 2009 (Estimated) |
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| Awarded Amount to Date: |
$662000 |
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| Investigator(s): |
David Laidlaw dhl@cs.brown.edu (Principal Investigator)
Sharon Swartz (Co-Principal Investigator) Peter Richardson (Co-Principal Investigator) George Karniadakis (Co-Principal Investigator)
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| Sponsor: |
Brown University
BOX 1929
Providence, RI 02912 401/863-2777
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| NSF Program(s): |
UNDISTRIBUTED PANEL/IPA FUNDS, ITR FOR NATIONAL PRIORITIES, INFORMATION TECHNOLOGY RESEARC
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| Field Application(s): |
0000912 Computer Science
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| Program Reference Code(s): |
HPCC, 9251, 9218, 9150, 7354, 2884
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| Program Element Code(s): |
9199, 7314, 1640
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ABSTRACT

This project is to discover new distributed simulation, visualization, and analysis tools for interacting with and understanding multi-valued volumes of scientific data and the biological phenomena they measure. The tools will be developed and evaluated in close collaboration with biologists studying three independent flow-related problems: coronary artery lesion and thrombus formation, the mechanisms and evolution of bat flight, and the mechanism and evolution of fish propulsion and maneuvering.
The work includes advancing basic scientific understanding in the three biological application areas. In addition, the experimental methodology of acquiring 3D motion and flow data using 3D Digital Particle Image Velocimetry (DPIV) and high-speed video will advance the state of the art for studying flow interactions with other biological and man-made systems and may be used for prediction, risk-assessment and decision-making.
The simulation and modeling work to address the biological problems will create new simulation methods for coupling unsteady flow and structure calculations, new methods for incorporating uncertainty into unsteady simulation results, new methods for combining unsteady experimental and simulation data to facilitate comparisons between them, and new methods for filling in gaps in unsteady experimental data.
PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH

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(Showing: 1 - 21 of 21)
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Cagatay Demiralp, Cullen Jackson, David Karelitz, Song Zhang and David H. Laidlaw. "CAVE and Fishtank Virtual-Reality Displays: A Qualitative and Quantitative Comparison," IEEE Transaction on Visualization and Computer Graphics, v.12, 2006, p. 323.
Daniel Acevedo and David H. Laidlaw. "Subjective Quatification of Perceptual Interactions among some 2D Scientific Visualization Methods," Transaction of Visualization and Computer Graphics. IEEE Visualization 2006, 2006, p. ?.
Daniel Acevedo, Cullen Jackson, David H. Laidlaw, and Fritz Drury. "Using Visual Design Expertise to Characterize the Effectiveness of 2D Scientific Visualization Methods," IEEE Visualization, 2005 Poster Compendium, 2005, p. ?.
Daniel Acevedo, Cullen Jackson, David H. Laidlaw, and Fritz Drury. "Using Visual Design Experts in Critique-based Evaluation of 2D Vector Visualization Methods," IEEE Transactions on Visualization and Computer Graphics, 2008.
Daniel Acevedo, Jian Chen, and David H. Laidlaw. "Modeling Perceptual Dominance Among Visual Cues in Multilayered Icon-based Scientific Visualizations," IEEE Visualization'07, Poster Compendium, 2007.
Daniel Keefe and David H. Laidlaw. "A Haptic Interface for Creating Smooth 3D Curves with Varying Line Weight," ACM SIGGRAPH 2005 Posters Program, 2005, p. ?.
Daniel Keefe, Daniel Acevedo, Jadrian Miles, Fritz Drury, Sharon Swartz, and David H. Laidlaw. "Scientific Sketching for Collaborative VR Visualization Design," IEEE Transactions on Visualization and Computer Graphics, 2008.
Daniel Keefe, David Karelitz, Eileen Vote, and David H. Laidlaw. "Artistic collaboration in designing VR visualizations.," IEEE Computer Graphics and Applications, v.25, 2005, p. 18.
Daniel Riskin, David Willis, Jose Iriarte-Diaz, Tyson Hedrick, Mykhaylo Kostandov, Jian Chen, David H. Laidlaw, Kenneth Brueur, and Sharon Swartz. "Quantifying the complexity of bat-wing dynamics," Journal of Theoretical Biology, 2008.
Don House, Vistoria interrante, David H. Laidlaw, Russel Taylor and Colin Ware. "Panel: Design and Evaluation in Visualization Research," IEEE Visualization 2006, 2006, p. ?.
E.L. Dumon and Sharon Swartz. "Biomechanical approaches and ecological research," Ecological and Behavioral Methods for the Study of Bats, 2006.
Igor Pivkin, Eduardo Hueso, Rachel Weinstein, David H. Laidlaw, Sharon Swartz, and George E. Karniadakis. "Simulation and visualization of air flow around bat wings during flight," In Proceedings of International Conference
on Computational Science, 2005, p. ?.
Igor Pivkin, Peter Richardson, David H. Laidlaw, and George Karniadakis. "Combined effects of pulsatile flow and
dynamic curvature on wall shear stress in a coronary artery bifurcation model," Journal of Biomechanics,, 2004, p. ?.
Jian Chen, Andrew Forsberg, Mykhaylo Kostandov, Dave Willis, and David H. Laidlaw. "The Effect of Using Large, High-Resolution Stereoscopic Displays for Flow Visualization," SIGGRAPH poster, 2007.
Liew S, Man A, Parente J, Samaroo H, Stoner I, Richardson PD. "Adhesion and rouleau formation of red cells in a shear flow," 33rd Northeast Bioengineering Conf, 2007, p. 179.
Peter Richardson, Igor Pivkin, and George Karniadakis. "Red cells in shear flow: Dissipative particle dynamics modeling," Biorheology, 2008.
Peter Richardson, Igor Pivkin, George Karniadakis, and David H. Laidlaw. "Blood Flow at Arterial Branches: Complexities to Resolve for the Angioplasty Suite," Proceedings of international Conference of Computational Science. Workshop on Dynamic Data Driven Application Systems, 2006, p. ?.
Pivkin IV, Richardson PD, Karniadakis G.. "Blood flow velocity effects and role of activation delay time on growth and form of platelet thrombi," Proc Nat Acad Sci., 2006.
Pivkin IV, Richardson PD, Karniadakis GE. "Effect of presence or absence of red cells on early growth rates of platelet mural thrombi," J Thromb Haemost, 2007.
R. Galvao, E. Israeli, A. Song, X. Tian, K. Bishop, Sharon Swartz, and Kenneth Breuer. "The Aerodynamics of Compliant Membrane Wings Modeled on Mammalian Flight Mechanics," Proceedings of 36th AIAA Fluid Dynamics Conference, 2006, p. ?.
X. Tian, J. Iriarte, K. Middleton, R. Galvao, E. Israeli, A. Roemer, A. Sullivan, A. Song, Sharon Swartz, and Kenneth Breuer. "Direct Measurements of the Kinematics and Dynamics of Bat Flight," Proceedings of 36th AIAA Fluid Dynamics Conference, 2006, p. ?.
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