 |
|
|
Award Abstract #0427657
SENSORS: Photonic Crystal Biosensors
| NSF Org: |
CBET
Division of Chemical, Bioengineering, Environmental, and Transport Systems
|
|
|
| Initial Amendment Date: |
July 22, 2004 |
|
| Latest Amendment Date: |
July 22, 2004 |
|
| Award Number: |
0427657 |
|
| Award Instrument: |
Standard Grant |
|
| Program Manager: |
Leon Esterowitz
CBET Division of Chemical, Bioengineering, Environmental, and Transport Systems
ENG Directorate for Engineering
|
|
| Start Date: |
September 1, 2004 |
|
| Expires: |
August 31, 2008 (Estimated) |
|
| Awarded Amount to Date: |
$365223 |
|
| Investigator(s): |
Brian Cunningham bcunning@illinois.edu (Principal Investigator)
|
|
| Sponsor: |
University of Illinois at Urbana-Champaign
SUITE A
CHAMPAIGN, IL 61820 217/333-2187
|
|
| NSF Program(s): |
BIOMEDICAL ENGINEERING
|
|
| Field Application(s): |
0000099 Other Applications NEC
|
|
| Program Reference Code(s): |
OTHR, 7224, 0000
|
|
| Program Element Code(s): |
5345
|
ABSTRACT
0427657
Cunningham
This project will take advantage of recent advances in nanofabrication tools, novel materials, and mathematical modeling methods to produce high sensitivity biosensors and arrays with substantially higher performance and significantly greater application space than first generation devices. This will allow array spatial resolution of less than one micron, representing the capability to resolve the adsorption of individual protein molecules to the sensor surface.
PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH
|
(Showing: 1 - 10 of 13)
(Showing: 1 - 13 of 13)
|
Show All |
C. J. . Choi and B.T. Cunningham. "A 96-well microplate incorporating a replica molded microfluidic network integrated with
photonic crystal biosensors for high throughput kinetic biomolecular interaction analysis," Lab on a Chip, v.7, 2007, p. 550.
C.J. Choi and B.T. Cunningham. "Single step fabrication of photonic crystal biosensors with polymer microfluidic channels by a
replica molding process," Lab On a Chip, v.6, 2006, p. 1373.
I. Block, L. Chan, and B.T. Cunningham. "Photonic Crystal Optical Biosensor Incorporting Structured Low-Index Porous Dielectric," Sensors and Actuators B, v.120, 2006, p. 187.
I.D. Block, L.L. Chan, and B.T. Cunningham. "Large-area submicron replica molding of porous low-k dielectric films and applications to
photonic crystal biosensor fabrication," Microelectronic Engineering, v.84, 2007, p. 603.
L.L. Chan, M.F. Pineda, J. Heeres, P. Hergenrother, and B T. Cunningham. "General Method for Discovering Inhibitors of Protein-DNA Interactions using Photonic Crystal Biosensors," Chemical Biology, v.3, 2008, p. 437.
L.L. Chan, P.Y. Li, D. Puff, and B.T. Cunningham. "A self- referencing method for microplate label-free photonic crystal biosensors," IEEE Sensors Journal, v.6, 2006, p. 1551.
L.L. Chan, P.Y. Li, D. Puff, and B.T. Cunningham. "Self-referenced assay method for photonic crystal biosensors: application to small molecule
analytes," Sensors and Actuators B, v.120, 2007, p. 392.
N. Ganesh and B.T. Cunningham. "Photonic crystal near UV reflectance filters fabricated by nano replica molding," Applied Physics Letters, v.88, 2006, p. 071110.
N. Ganesh, I. Block, and B.T. Cunningham. "UV-wavelength photonic-crystal biosensor with enhanced surface-to-bulk sensitivity ratio," Applied Physics Letters, v.89, 2006, p. 023901.
N. Ganesh, W. Zhang, P.C. Mathias and B.T. Cunningham. "Enhanced fluorescence emission from quantum dots on a photonic crystal surface," Nature Nanotechnology, v.2, 2007, p. 515.
N.Ganesh, A. Xiang, N.B. Beltran, D.W. Dobbs, and B.T. Cunningham. "Compact Wavelength Detection System Incorporating a Guided-Mode Resonance Filter," Applied Physics Lettera, v.90, 2007, p. 081103.
P.C. Mathias, N. Ganesh, I.D. Block, and B.T. Cunningham. "Combined Enhanced Fluorescence and Label-Free Biomolecular Detection with a Photonic
Crystal Surface," Applied Optics, v.26, 2007, p. 2351.
W. Zhang, N. Ganesh, I.D. Block and B.T. Cunningham. "High Sensitivity Photonic Crystal Biosensor Incorporating Nanorod Structures for Enhanced Surface Area," Sensors and Actuators B, v.13, 2008, p. 279.
|
(Showing: 1 - 10 of 13) (Showing: 1 - 13 of 13) |
Show All |
Please report errors in award information by writing to: awardsearch@nsf.gov.
|
|
|
