Award Abstract #0754122
Photonic Crystal Enhanced Fluorescence

NSF Org:	CBET Division of Chemical, Bioengineering, Environmental, and Transport Systems
Initial Amendment Date:	February 7, 2008
Latest Amendment Date:	February 7, 2008
Award Number:	0754122
Award Instrument:	Standard Grant
Program Manager:	Leon Esterowitz CBET Division of Chemical, Bioengineering, Environmental, and Transport Systems ENG Directorate for Engineering
Start Date:	August 1, 2008
Expires:	July 31, 2011 (Estimated)
Awarded Amount to Date:	$350612
Investigator(s):	Brian Cunningham bcunning@illinois.edu (Principal Investigator)
Sponsor:	University of Illinois at Urbana-Champaign SUITE A CHAMPAIGN, IL 61820 217/333-2187
NSF Program(s):	BIOPHOTONICS, IMAGING &SENSING
Field Application(s):	0000099 Other Applications NEC
Program Reference Code(s):	OTHR, 7237, 005E, 0000
Program Element Code(s):	7236

ABSTRACT

0754122

Cunningham

The proposal describes a basic design for a 2-dimensional surface photonic crystal and shows how such a structure provides high Q-factor optical resonances with enhanced near fields at a precisely defined wavelength. Using devices designed for excitation of the fluorophore Cy5 or for semiconductor quantum dots, they propose characterization of the enhanced excitation effects spatial distribution and the design/fabrication of structures with optimal capability to take advantage of enhanced excitation through higher Q and/or redistribution of the resonant modes. They propose to characterize the enhanced extraction effect using various geometrical arrangements of the photonic crystal lattice, and the development of materials and fabrication approaches resulting in optimal signal/noise. They plan to combine label-free photonic crystal biosensor detection with enhanced fluorescence on the same surface, enabling dual-mode imaging detection that can discriminate between labeled and non-labeled analytes.

PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH

N. Ganesh, I.D. Block, P.C. Mathias, W. Zhang, E. Chow, V. Malyarchuk, and B.T. Cunningham. "Leaky-mode assisted fluorescence extraction: Application to fluorescence enhancement biosensors,," Optics Express, v.16, 2008, p. 21626.

P.C. Mathias, N. Ganesh, and B.T. Cunningham. "Application of Photonic Crystal Enhanced Fluorescence to a Cytokine Immunoassay," Analytical Chemistry, v.80, 2008, p. 9013.

W. Zhang and B.T. Cunningham. "Fluorescence enhancement by a photonic crystal with a nanorod-structured high index layer," Applied Physics Letters, v.93, 2008, p. 133115.

W. Zhang, N. Ganesh, P.C. Mathias, and B.T. Cunningham. "Enhanced fluorescence on a photonic crystal surface incorporating nanorod structures," Small, v.4, 2008, p. 2199.

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