Award Abstract #0820919
MRI: Acquisition of a Low-Field NMR for Research/Education at Texas A&M International University

NSF Org:	CBET Division of Chemical, Bioengineering, Environmental, and Transport Systems
Initial Amendment Date:	July 9, 2008
Latest Amendment Date:	July 9, 2008
Award Number:	0820919
Award Instrument:	Standard Grant
Program Manager:	Leon Esterowitz CBET Division of Chemical, Bioengineering, Environmental, and Transport Systems ENG Directorate for Engineering
Start Date:	September 1, 2008
Expires:	August 31, 2011 (Estimated)
Awarded Amount to Date:	$99210
Investigator(s):	Qingwen Ni qni@tamiu.edu (Principal Investigator) Hoonandara Goonatilake (Co-Principal Investigator) Fuming Wu (Co-Principal Investigator) Runchang Lin (Co-Principal Investigator) Tongdan Jin (Co-Principal Investigator)
Sponsor:	Texas A&M International University 5201 University Boulevard Laredo, TX 78041 956/326-2320
NSF Program(s):	MAJOR RESEARCH INSTRUMENTATION
Field Application(s):	0000099 Other Applications NEC
Program Reference Code(s):	OTHR, 7236, 004E, 0000
Program Element Code(s):	1189

ABSTRACT

CBET-0820919

Ni

This proposal requests funding for a BRUKER low-field proton 7.5 MHz bench-top NMR

system for research and teaching. The main components of this 7.5 MHz TD-NMR Analyzer

with gradient capability are listed as following.

1. mg-YS-R/GX: mg7.5, 7.5 TD-NMR Analyzer

2. mg-HPC: Host personal computer

3. mg-PGU4: One dimensional Unipolar Gradient Amplifier

4. mg-ExpSpel: Developers' Software Option (operating NMR sequence program,

controlling data, etc.)

One of the objectives of the proposed research is to develop a non-destructive and noninvasive

technique to assess bone quality by quantifying the distribution of water (bound and mobile

water) within bone tissue, porosity, and pore size distributions in cortical bone in vitro. In

addition, the acquired instrumentation will provide other faculty with the necessary tool(s) to

pursue aspects of their research that are presently not available on the TAMIU campus.

PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH

Nyman, JS; Ni, QW; Nicolella, DP; Wang, XD. "Measurements of mobile and bound water by nuclear magnetic resonance correlate with mechanical properties of bone," BONE, v.42, 2008, p. 193-199. 

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