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Award Abstract #0303860

NER: Nano-Scale Volume Cells

Div Of Electrical, Commun & Cyber Sys
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Initial Amendment Date: July 7, 2003
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Latest Amendment Date: July 7, 2003
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Award Number: 0303860
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Award Instrument: Standard Grant
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Program Manager: Rajinder P. Khosla
ECCS Div Of Electrical, Commun & Cyber Sys
ENG Directorate For Engineering
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Start Date: July 15, 2003
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End Date: November 30, 2005 (Estimated)
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Awarded Amount to Date: $100,000.00
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Investigator(s): Peter Will will@isi.edu (Principal Investigator)
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Sponsor: University of Southern California
University Park
Los Angeles, CA 90089-0001 (213)740-7762
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Program Reference Code(s): 0000, 1676, OTHR
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Program Element Code(s): 1517


VOXEL is focused on investigating the feasibility of building hollow, 3-D, programmable-volume, nano-scale, artificial, non-biological volume-cells or voxels. The aim is to make a shell to encapsulate nano-scale quantities of various materials. The target size is of the order of 30 to 100 nanometers in diameter, much bigger than a supra-molecule made by organic chemistry, but much smaller than MEMS structures; small enough in fact to allow traversal through the pores of biological membranes. This has never been done before.

The proposed work is a one-year EXPLORATORY project and will focus, following an origami-inspired strategy, on making the basic planar shaped platelets of the right size and shape that in later work will be raised from the plane to join to make the desired volume. Pentagonal platelets, the basis of a dodecahedral shell, will be made in this one year plan, from assemblies of 5 and 10 n meter gold spheres using a Scanning Probe

Microscope and then fused by plating. Successful results will give a good basis for focused collaborations with colleagues from a wide variety of scientific disciplines most certainly including medicine, in order to explore the biological implications including specifically the extension to the use of bio-compatible materials.


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