text-only page produced automatically by Usablenet Assistive Skip all navigation and go to page content Skip top navigation and go to directorate navigation Skip top navigation and go to page navigation
National Science Foundation
Awards
design element
Search Awards
Recent Awards
Presidential and Honorary Awards
About Awards
Grant Policy Manual
Grant General Conditions
Cooperative Agreement Conditions
Special Conditions
Federal Demonstration Partnership
Policy Office Website



Award Abstract #1229021

MRI: Acquisition of a 400 MHz NMR Spectrometer to Enhance Undergraduate and Faculty Research

NSF Org: CHE
Division Of Chemistry
divider line
Initial Amendment Date: August 31, 2012
divider line
Latest Amendment Date: August 31, 2012
divider line
Award Number: 1229021
divider line
Award Instrument: Standard Grant
divider line
Program Manager: Carlos A. Murillo
CHE Division Of Chemistry
MPS Direct For Mathematical & Physical Scien
divider line
Start Date: September 1, 2012
divider line
End Date: August 31, 2015 (Estimated)
divider line
Awarded Amount to Date: $285,000.00
divider line
Investigator(s): Mary O'Sullivan osulliv1@canisius.edu (Principal Investigator)
Jeremy Steinbacher (Co-Principal Investigator)
Mariusz Kozik (Co-Principal Investigator)
Sarah Evans (Co-Principal Investigator)
Timothy Gregg (Co-Principal Investigator)
divider line
Sponsor: Canisius College
2001 Main Street
Buffalo, NY 14208-1098 (716)888-2103
divider line
NSF Program(s): MAJOR RESEARCH INSTRUMENTATION
divider line
Program Reference Code(s): 1108, 1189, 1401, 1982, 6884
divider line
Program Element Code(s): 1189

ABSTRACT

With this award from the Major Research Instrumentation Program, Professor Mary O'Sullivan from Canisius College and colleagues Mariusz Kozik, Timothy Gregg, Jeremy Steinbacher and Sarah Evans will acquire a 400 MHz NMR spectrometer. The proposal is aimed at enhancing research training and education at all levels, especially in areas such as (a) development of particle-based contrast agents for fluorine MRI; (b) investigations of organic mechanisms and methodologies (allene cyclopropanation); (c) development of inhibitors of an enzyme (trypanothione reductase) in parasites; (d) studies of the interactions of polyamines with the N-methyl-D-aspartate (NMDA) receptor; (e) investigations of DNA-protein cross-links; (f) studies to elucidate the structures of inorganic complexes (transition-metal substituted heteropolytungstates); and (g) uses of inorganic complexes as photo-activated catalysts for reduction reactions.

Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument will be an integral part of teaching as well as research at Canisius College and neighboring institutions.


PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH

Note:  When clicking on a Digital Object Identifier (DOI) number, you will be taken to an external site maintained by the publisher. Some full text articles may not yet be available without a charge during the embargo (administrative interval).

Some links on this page may take you to non-federal websites. Their policies may differ from this site.


Adam Dannenhoffer, Jerry Baker, Nicholas Pantano, Jessica Stachowski, Derek Zemla, Eva Zurek, Steven Szczepankiewicz and Mariusz Kozik*. "?Dimerization of Cobalt Substituted Keggin Phosphotungstate, [PW11O39Co(X)]5-, in Nonpolar Solvents?," Journal of Coordination Chemistry, v.67, 2014, p. 2830. 

Mary O'Sullivan*, Timothy Durham, Hannah Valdes, Kelly Dauer, Nicholas Karney, Andrew Forrestel, Cyrus Bacchi, Jerome Baker. ""Dibenzosuberyl substituted polyamines and analogs of clomipramine as effective inhibitors of trypanothione reductase; molecular docking, and assessment of trypanocidal activities"," Bioorganic and Medicinal Chemistry, v.23, 2015, p. 996. 

 

Please report errors in award information by writing to: awardsearch@nsf.gov.

 

 

Print this page
Back to Top of page
  FUNDING   AWARDS   DISCOVERIES   NEWS   PUBLICATIONS   STATISTICS   ABOUT NSF   FASTLANE  
Research.gov  |  USA.gov  |  National Science Board  |  Recovery Act  |  Budget and Performance  |  Annual Financial Report
Web Policies and Important Links  |  Privacy  |  FOIA  |  NO FEAR Act  |  Inspector General  |  Webmaster Contact  |  Site Map
National Science Foundation Logo
The National Science Foundation, 4201 Wilson Boulevard, Arlington, Virginia 22230, USA
Tel: (703) 292-5111, FIRS: (800) 877-8339 | TDD: (800) 281-8749
  Text Only Version