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Award Abstract #1229309

MRI: Acquisition of a Fluorescence Activated Cell Sorter (FACS)

NSF Org: CBET
Div Of Chem, Bioeng, Env, & Transp Sys
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Initial Amendment Date: August 9, 2012
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Latest Amendment Date: July 30, 2014
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Award Number: 1229309
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Award Instrument: Standard Grant
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Program Manager: Leon Esterowitz
CBET Div Of Chem, Bioeng, Env, & Transp Sys
ENG Directorate For Engineering
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Start Date: August 15, 2012
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End Date: July 31, 2015 (Estimated)
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Awarded Amount to Date: $394,343.00
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Investigator(s): Vassilios Sikavitsas vis@ou.edu (Principal Investigator)
David Schmidtke (Former Principal Investigator)
Anne Dunn (Co-Principal Investigator)
Chuanbin Mao (Co-Principal Investigator)
Binil Starly (Former Co-Principal Investigator)
Vassilios Sikavitsas (Former Co-Principal Investigator)
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Sponsor: University of Oklahoma Norman Campus
201 Stephenson Parkway
NORMAN, OK 73019-9705 (405)325-4757
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NSF Program(s): MAJOR RESEARCH INSTRUMENTATION
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Program Reference Code(s): 004E, 044E
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Program Element Code(s): 1189

ABSTRACT

This proposal is for the acquisition of a state-of-the-art Fluorescence Activated Cell Sorter (FACS) that will become part of a flow cytometry/cell sorting shared use facility appealing to a diverse set of research programs on the University of Oklahoma (OU) campus in Norman. Cell sorting is recognized as important and indispensable tools in fields ranging from basic biology in the life sciences to translational biomedical engineering research. Acquisition of state-of-the-art cell sorting capabilities on the OU-Norman campus would not only make available needed resources, but would also provide a powerful complement to existing cellular characterization facilities on the OU-Norman Campus: Scanning Electron Microscopy, Multi-photon Laser Scanning Confocal Microscopy, and Atomic Force Microscopy. Combining detailed information about individual cell structures provided by these microscopy techniques with (i) the extensive statistical information about cell populations from high throughput flow cytometry and (ii) the ability to identify and sort cells from complex populations by immunophenotyping will foster new and innovative research directions across the OU campus.

 

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