Carlos A. Murillo CHE Division Of Chemistry
MPS Direct For Mathematical & Physical Scien
September 1, 2012
August 31, 2015 (Estimated)
Awarded Amount to Date:
Victoria Moore email@example.com (Principal Investigator)
Karl Sienerth (Co-Principal Investigator) Kathryn Matera (Co-Principal Investigator)
2610 Campus Box
MAJOR RESEARCH INSTRUMENTATION
Program Reference Code(s):
1108, 1189, 1982, 9156
Program Element Code(s):
With this award from the Major Research Instrumentation (MRI) program, Professor Victoria Moore from Elon University and colleagues Karl Sienerth and Kathryn Matera will acquire a multimode quad-monochromator plate reader spectrophotometer. The proposal is aimed at enhancing research training and education, especially in areas such as (a) peptide aggregates; (b) protein-protein binding; (c) biochemical changes to mitochondria during apoptosis; and (d) quantitative measurements of environmental and explosive compounds.
This award will provide a multimode spectrophotometer to make absorbance, fluorescence and luminescence measurements on various samples. These are standard spectroscopy techniques used to assay small volumes of solutions in chemistry and biochemistry. Reactions can be followed and quantities of materials determined. This acquisition will provide a basic instrument for current biochemistry and chemistry research by faculty and undergraduate students. Students will be trained to use the most up-to-date assays and technologies which they will encounter after graduation.
PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH
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Bedard M, Giffear KA, Ponton L, Sienerth KD, Del Gaizo Moore V.. "Characterization of binding between 17?-estradiol and estriol with humic acid via NMR and biochemical analysis.," Biophysical Chemistry, v.189, 2014, p. 1.
Fischer, A.*, Mansfield Matera, K.. "Stabilization of Alpha-Synuclein Oligomers In Vitro by the Neurotransmitters, Dopamine and Norepinephrine: The Effect of Oxidized Catecholamines.," Neurochem Res., v.40, 2015, p. 1341.
Lampl, T., Davis, T. Crum, J.A., Milligan, C. and Del Gaizo Moore, V.. "Isolation and functional analysis of mitochondria from cultured cells and mouse tissue.," Journal of Visual Experimentation, v.97, 2015, p. e52076.
Bedard, M.E., Giffear, K.A., Ponton, L., Sienerth, K., and Del Gaizo Moore, V.. "Characterization of binding between 17?-estradiol and estriol with humic acid via NMR and biochemical analysis.," Biophysical Chemistry, v.189, 2014, p. 1.