Colby A. Foss CHE Division Of Chemistry
MPS Direct For Mathematical & Physical Scien
September 1, 2013
August 31, 2017 (Estimated)
Awarded Amount to Date:
Paul Champion firstname.lastname@example.org (Principal Investigator)
360 HUNTINGTON AVE
PHYSICS OF LIVING SYSTEMS,
Chem Struct,Dynmcs&Mechansms A
Program Reference Code(s):
1982, 7722, 8007, 9161, AMPP
Program Element Code(s):
7246, 7275, 9101
In this award, funded by the Chemical Structure, Dynamics, and Mechanisms Program (A) of the Division of Chemistry, the Molecular Biophysics Program of the Division of Molecular and Cellular Biosciences, and the Physics of Living Systems Program of the Division of Physics, Prof. Paul M. Champion at Northeastern University will use modern, ultrafast laser methods to study the ways in which biomolecular systems use thermal energy to carry out and control biochemical reactions. In particular, Prof. Champion and his research group will use vibrational coherence spectroscopy (VCS) and femtosecond stimulated Raman scattering (FSRS) will be used to probe the ways in which low-frequency vibrations of complex biomolecules influence or modify the reactivity of large biomolecules.
Understanding the chemical reactivity of biomolecular systems is critical towards understanding the way that biological systems operate at the macroscopic scale. Advances in this field will yield advances in medicine and biotechnology. The undergraduate and graduate students working with Prof. Champion will receive excellent training in cutting-edge science at the intersection of Biology and the Physical Sciences. Prof. Champion is also actively collaborating with scientists from underrepresented groups at Northeastern as well as in Puerto Rico.
PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH
Note: When clicking on a Digital Object Identifier (DOI) number, you will be taken to an external site maintained by the publisher. Some full text articles may not yet be available without a charge during the embargo (administrative interval).
Some links on this page may take you to non-federal websites. Their policies may differ from this site.
Venugopal Karunakaran, Yuhan Sun, Abdelkirm Benabbas, and Paul M. Champion. "?Investigations of the Low Frequency Modes of Ferric Cytochrome c Using Vibrational Coherence Spectroscopy?," J. Phys. Chem. B, v.118, 2014, p. 6062-6070.
Yuhan Sun, Abdelkirm Benabbas, Weiqiao Zeng, Jesse G. Kleingardner, Kara L. Bren, and Paul M. Champion. "?Investigations of Heme Distortion, Low-Frequency Vibrational Excitations, and Electron Transfer in Cytochrome c?,," Proc. Natl. Acad. Sci.(USA), v.111, 2014, p. 6570-6575.
Abdelkrim Benabbas, Bridget Salna, J. Timothy Sage, and Paul M. Champion. "Deep Proton Tunneling in the Electronically Adiabatic and Non-adiabatic Limits: Comparison of the Quantum and Classical Treatment of Donor-Acceptor Motion," J. Chem. Phys., v.142, 2015, p. 114101.