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Award Abstract #9980792

Photosynthesis based light transduction on a retinal prosthetic chip: Interfacing molecular reactions centers, nano-channel glass, and the retina

NSF Org: ECCS
Div Of Electrical, Commun & Cyber Sys
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Initial Amendment Date: September 29, 1999
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Latest Amendment Date: August 11, 2000
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Award Number: 9980792
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Award Instrument: Continuing grant
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Program Manager: James Momoh
ECCS Div Of Electrical, Commun & Cyber Sys
ENG Directorate For Engineering
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Start Date: September 15, 1999
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End Date: May 31, 2003 (Estimated)
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Awarded Amount to Date: $520,000.00
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Investigator(s): Mark Humayun humayun@usc.edu (Principal Investigator)
Brian Justus (Co-Principal Investigator)
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Sponsor: Johns Hopkins University
3400 N CHARLES ST
Baltimore, MD 21218-2608 (410)516-8668
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NSF Program(s): INTEGRATIVE SYSTEMS,
BIOMEDICAL ENGINEERING
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Program Reference Code(s): 0000, 1602, OTHR
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Program Element Code(s): 1519, 5345

ABSTRACT

This project will study interactions between three distinct systems: (1) photovoltaic molecules and/or membrane structures derived from green plants and artificial photosynthetic systems, (2) micron-scale electrode arrays formed by metal wires in microchannel glass, and (3) the retina. The proposed research will provide a knowledge and technology base necessary to integrate these systems towards the successful development of a novel, energy-efficient retinal prosthesis with a micron scale spatial resolution. More specifically, these objectives will be pursued:

- Investigate interactions between natural and artificial photoactive structures and microchannel glass electrode arrays and to determine methods of attaching the structures to individual microwires.

- Develop methods for depositing conductors throughout the entire length of the microchannels.

- Determine the optimal size and shape for a retinal stimulating electrode.

- Test the biocompatibility of the microchannel glass and photoactivated microchannel glass.

Results of this research are likely to have broader application through improved understanding of metal/molecular interfaces, imaging technology, novel microfabrication techniques, and biological interfacing and testing.

 

Please report errors in award information by writing to: awardsearch@nsf.gov.

 

 

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