In the initial planning document, it was estimated that approximately $400 million would be needed to
accomplish the goals set by the IWG in 1998 for the NPGI. In the past five years, NSF, DOE and USDA
have expended approximately $350 million. These investments have opened new and exciting research
opportunities. Expanded opportunities are now available to a large segment of the plant sciences research
community interested in genomics of diverse plants beyond a few key model plant
species. In order to fully capitalize on the investments made to date and to enable further advances in plant genome research, the
IWG recommends continued investment in the NPGI by all participating agencies. The IWG currently
estimates that achievement of the objectives outlined in this five-year plan could be accomplished
through an investment, over the next five years, of approximately $1.3 billion total as follows. These estimates,
which are subject to future change and refinement, do not represent a commitment to specific or
cumulative resource levels by the Federal government or any other partners in annual budget proposals.
$400M for generating sequences and sequence resources for genome structure and organizational
studies will result in the production of: (1) a completely finished rice genome sequence; (2) completely
finished and mapped sequences of gene-rich regions of the maize genome; (3) highly accurate draft
sequences of gene-rich regions of several key plant species; and (4) a variety of genome analysis tools
to study structure and organization of a large number of plant species of economic importance.
$200M for functional genomics studies will allow US scientists to participate in international projects
to determine the function of all of the genes in Arabidopsis and rice. The resulting functional genomics
research resources will be shared freely and quickly, building a foundation for functional genomics
research for all plant species.
$300M for translational genomics studies will enable a broad community of scientists to begin
applying the knowledge, resources and tools of genomics to understand the fundamental biology
of plants and the underlying mechanisms for economically important plant processes.
$250M for data management and informatics tools development will enable a broad community of
both basic and applied scientists to utilize the outcomes of NPGI research activities. $250M is a
conservative estimate since all plant genome research activities described above will include
informatics as an integral component, and thus the actual expenditure for data management and
informatics will be considerably higher.
$125M for training, education and outreach will allow establishment of a NPGI training grant
program and incorporation of training activities in all NPGI research activities.
The above budget estimates and distribution are based on the current state of science and technology in
plant genomics. Continued advances in technology are expected to decrease costs in some areas, while new technologies and unexpected opportunities
will necessitate increased investments in other areas. The Interagency
Working Group will continue to monitor and report annually the constantly
changing opportunities and needs to maintain effective and efficient
utilization of resources in this coordinated national research program.