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News From the Field
Bone's Material Flaws Lead to Disease
August 4, 2009
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The weak tendons and fragile bones characteristic of osteogenesis imperfecta, or brittle bone disease, stem from a genetic mutation that causes the incorrect substitution of a single amino acid in the chain of thousands of amino acids making up a collagen molecule, the basic building block of bone and tendon.
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Source
Massachusetts Institute of Technology
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