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News From the Field
Cell Surface Transporters Exploited for Cancer Drug Delivery

December 2, 2012

News thumbnail According to Whitehead Institute researchers, a protein known as monocarboxylate transporter 1 (MCT1), which is highly expressed in a subset of metabolically altered cancer cells, is needed for the entry of the investigational cancer drug 3-bromopyruvate (3-BrPA) into malignant cells. This work may open a new avenue for cancer therapeutic research, as other transport molecules have already been identified on the surface of certain cancer cells. Full Story

Source
Whitehead Institute for Biomedical Research

The National Science Foundation (NSF) is an independent federal agency that supports fundamental research and education across all fields of science and engineering. In fiscal year (FY) 2014, its budget is $7.2 billion. NSF funds reach all 50 states through grants to nearly 2,000 colleges, universities and other institutions. Each year, NSF receives about 50,000 competitive requests for funding, and makes about 11,500 new funding awards. NSF also awards about $593 million in professional and service contracts yearly.

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