News From the Field
A better way to purify peptide-based drugs
February 14, 2014
During the production of peptide drugs, amino acids attach to each other in chains, but some of the chains are never completed. To separate these truncated peptides from the good ones, Shiyue Fang of Michigan Tech and his team adds a polymerizable group of atoms to the mix. These atoms bind to either the perfect peptides or the unfinished ones, but not to both. The polymerized peptides become insoluble and precipitate out of the solution.
Michigan Technological University
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