| CHI Patent Family |
Earliest Pub Year |
Priority Country |
Standardized Assignee |
Country |
Representative Patent |
Representative Title |
Citation Index |
Cites Received |
| CHI00053 |
1999 |
EP |
Isotis Bv |
US |
6228117 |
Device for tissue engineering
bone |
7.50 |
11 |
| CHI00166 |
1990 |
US |
Advanced Tissue Sciences Inc |
US |
4963489 |
THREE-DIMENSIONAL CELL AND
TISSUE CULTURE SYSTEM |
5.73 |
162 |
| CHI00190 |
1996 |
US |
University Of Texas |
US |
5529914 |
Gels for encapsulation of
biological materials |
5.32 |
48 |
| CHI00163 |
1991 |
US |
Childrens Hospital |
US |
5041138 |
Neomorphogenesis of cartilage
in vivo from cell culture |
4.86 |
119 |
| CHI00070 |
1999 |
FR |
C R Bard Inc |
US |
5954767 |
Curved prosthetic mesh and its
method of manufacture |
4.77 |
7 |
| CHI00352 |
1999 |
US |
University Of Michigan |
US |
5885829 |
Engineering oral tissues |
4.77 |
7 |
| CHI00051 |
1999 |
EP |
Roche Holding Ltd |
EP |
897010 |
Modified phytases |
4.09 |
6 |
| CHI00376 |
1999 |
US |
Keraplast Technologies Ltd |
US |
5932552 |
Keratin-based hydrogel for
biomedical applications and method of production |
4.09 |
6 |
| CHI00259 |
1998 |
US |
Organogenesis Inc |
US |
5733337 |
Tissue repair fabric |
3.94 |
18 |
| CHI00173 |
1993 |
US |
** Unassigned ** |
US |
5226914 |
Method for treating connective
tissue disorders |
3.88 |
66 |
| CHI00099 |
1991 |
US |
Advance Tissue Sciences Inc |
US |
5032508 |
Three-dimensional cell and
tissue culture system |
3.80 |
93 |
| CHI00200 |
1995 |
US |
Rice Univ |
US |
5522895 |
Biodegradable bone templates |
3.78 |
38 |
| CHI00172 |
1993 |
US |
** Unassigned ** |
US |
5197985 |
Method for enhancing the
implantation and differentiation of marrow-derived mesenchymal cells |
3.59 |
61 |
| CHI00180 |
1993 |
US |
Regen Biologics Inc |
US |
5306311 |
Prosthetic articular cartilage |
3.53 |
60 |
| CHI00302 |
1997 |
US |
N Shore Univ Hospital Research Corp |
US |
5700289 |
Tissue-engineered bone repair
using cultured periosteal cells |
3.46 |
21 |
| CHI00274 |
1999 |
US |
Cryolife Inc |
US |
5899936 |
Treated tissue for implantation
and methods of preparation |
3.41 |
5 |
| CHI00335 |
1999 |
US |
Osteobiologics Inc |
US |
5863297 |
"Moldable, hand-shapable
biodegradable implant material" |
3.41 |
5 |
| CHI00265 |
1999 |
US |
Childrens Medical Center Corp |
US |
5855610 |
"Engineering of strong,
pliable tissues" |
3.41 |
5 |
| CHI00149 |
1989 |
US |
** Unassigned ** |
US |
4846835 |
TECHNIQUE FOR HEALING LESIONS
IN CARTILAGE |
3.19 |
102 |
| CHI00328 |
1997 |
US |
Advance Tissue Sciences Inc |
US |
5792603 |
"Apparatus and method for
sterilizing, seeding, culturing, storing, shipping and testing tissue,
synthetic or native, vascular grafts" |
3.13 |
19 |
| CHI00203 |
1995 |
US |
Advance Tissue Sciences Inc |
US |
5443950 |
Three-dimensional cell and
tissue culture system |
3.09 |
31 |
| CHI00330 |
1998 |
US |
Genzyme Corporation |
EP |
920490 |
CHONDROCYTE MEDIA FORMULATIONS
AND CULTURE PROCEDURES |
3.06 |
14 |
| CHI00329 |
1998 |
US |
Genzyme Corporation |
EP |
920490 |
CHONDROCYTE MEDIA FORMULATIONS
AND CULTURE PROCEDURES |
3.06 |
14 |
| CHI00196 |
1996 |
US |
Mit/Mass Inst Of Technology |
US |
5514378 |
Biocompatible polymer membranes
and methods of preparation of three dimensional membrane structures |
2.99 |
27 |
| CHI00213 |
1998 |
US |
Mass Inst Of Tech Childrens Med Ctr Corp |
US |
5770193 |
Preparation of
three-dimensional fibrous scaffold for attaching cells to produce
vascularized tissue in vivo |
2.84 |
13 |
| CHI00168 |
1998 |
US |
Mit/Mass Inst Of Technology |
US |
5736372 |
Biodegradable synthetic
polymeric fibrous matrix containing chondrocyte for in vivo production of a
cartilaginous structure |
2.84 |
13 |
| CHI00165 |
1991 |
US |
Grace (Wr) & Co |
US |
5002661 |
Artificial pancreatic perfusion
device |
2.82 |
69 |
| CHI00222 |
1997 |
US |
Mit/Mass Inst Of Technology |
US |
5626861 |
Polymeric-hydroxyapatite bone
composite |
2.80 |
17 |
| CHI00313 |
1997 |
US |
Advance Tissue Sciences Inc |
US |
5842477 |
Method for repairing cartilage |
2.80 |
17 |
| CHI00386 |
1999 |
US |
Advance Tissue Sciences Inc |
US |
6121042 |
Apparatus and method for
simulating in vivo conditions while seeding and culturing three-dimensional
tissue constructs |
2.73 |
4 |
| CHI00339 |
1999 |
US |
University Of Massachusetts |
US |
5944754 |
Tissue re-surfacing with
hydrogel-cell compositions |
2.73 |
4 |
| CHI00334 |
1999 |
US |
Case Western Reserve University |
US |
5855619 |
Biomatrix for soft tissue
regeneration |
2.73 |
4 |
| CHI00131 |
1984 |
US |
Mit/Mass Inst Of Technology |
US |
4485096 |
Tissue-equivalent and method
for preparation thereof |
2.50 |
127 |
| CHI00283 |
1997 |
US |
Focal Inc |
US |
5662712 |
Apparatus for intraluminal
photothermoforming |
2.47 |
15 |
| CHI00201 |
1996 |
US |
Mit/Mass Inst Of Technology |
US |
5567612 |
Genitourinary cell-matrix
structure for implantation into a human and a method of making |
2.44 |
22 |
| CHI00212 |
1998 |
US |
Mit/Mass Inst Of Technology |
US |
5759830 |
Three-dimensional fibrous
scaffold containing attached cells for producing vascularized tissue in vivo |
2.41 |
11 |
| CHI00224 |
1994 |
US |
Mit/Mass Inst Of Technology |
US |
5709854 |
Tissue formation by injecting a
cell-polymeric solution that gels in vivo |
2.40 |
35 |
| CHI00192 |
1995 |
US |
Mit/Mass Inst Of Technology |
US |
5399665 |
Biodegradable polymers for cell
transplantation |
2.29 |
23 |
| CHI00150 |
1989 |
US |
Regen Biologics Inc |
US |
4880429 |
PROSTHETIC MENISCUS |
2.28 |
73 |
| CHI00167 |
1992 |
US |
Northwestern University |
US |
5112354 |
Bone allograft material and
method |
2.27 |
47 |
| CHI00188 |
1994 |
US |
Boston Scientific Corp |
US |
5383925 |
Three-dimensional braided soft
tissue prosthesis |
2.26 |
33 |
| CHI00191 |
1995 |
US |
Advance Tissue Sciences Inc |
US |
5478739 |
Three-dimensional stromal cell
and tissue culture system |
2.19 |
22 |
| CHI00272 |
1995 |
US |
Advance Tissue Sciences Inc |
US |
5902741 |
Three-dimensional cartilage
cultures |
2.19 |
22 |
| CHI00288 |
1998 |
US |
Childrens Medical Center Corp |
US |
5741685 |
Parenchymal cells packaged in
immunoprotective tissue for implantation |
2.19 |
10 |
| CHI00214 |
1998 |
US |
Mass Inst Of Tech Childrens Med Ctr Corp |
US |
5770417 |
Three-dimensional fibrous
scaffold containing attached cells for producing vascularized tissue in vivo |
2.19 |
10 |
| CHI00044 |
1998 |
DK |
Novo Nordisk A/S |
EP |
937138 |
CELLULASE VARIANTS |
2.19 |
10 |
| CHI00287 |
1998 |
US |
Baxter International Inc |
US |
5741330 |
Close vascularization implant
material |
2.19 |
10 |
| CHI00346 |
1998 |
US |
Mit/Mass Inst Of Technology |
US |
5766618 |
Polymeric-hydroxyapatite bone
composite |
2.19 |
10 |
| CHI00239 |
1998 |
US |
Mit/Mass Inst Of Technology |
US |
5716404 |
Breast tissue engineering |
2.19 |
10 |
| CHI00142 |
1988 |
US |
Collagen Corp |
US |
4789663 |
Methods of bone repair using
collagen |
2.15 |
77 |
| CHI00095 |
1997 |
IT |
Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa |
EP |
846164 |
"METHODOLOGY TO PRODUCE,
PURIFY AND ASSAY POLYPEPTIDES WITH THE PROTEOLYTIC ACTIVITY OF THE HCV NS3
PROTEASE" |
2.14 |
13 |
| CHI00273 |
1997 |
US |
Cryolife Inc |
US |
5632778 |
Treated tissue for implantation
and methods of preparation |
2.14 |
13 |
| CHI00170 |
1993 |
US |
Advance Tissue Sciences Inc |
US |
5266480 |
Three-dimensional skin culture
system |
2.12 |
36 |
| CHI00130 |
1985 |
US |
Mit/Mass Inst Of Technology |
US |
4546500 |
FABRICATION OF LIVING BLOOD
VESSELS AND GLANDULAR TISSUES |
2.11 |
99 |
| CHI00277 |
1999 |
US |
** Unassigned ** |
US |
5916265 |
Method of producing a
biological extracellular matrix for use as a cell seeding scaffold and
implant |
2.05 |
3 |
| CHI00353 |
1999 |
US |
Brown University |
US |
5939323 |
Hyaluronan based biodegradable
scaffolds for tissue repair |
2.05 |
3 |
| CHI00365 |
1999 |
US |
Hadasit Medical Research Services And Development Ltd |
EP |
1015570 |
FIBRIN MICROBEADS AND USES
THEREOF |
2.05 |
3 |
| CHI00374 |
1999 |
US |
Advance Tissue Sciences Inc |
US |
5858721 |
Three-dimensional cell and
tissue culture system |
2.05 |
3 |
| CHI00426 |
1999 |
US |
Keraplast Technologies Ltd |
US |
5948432 |
Keratin-based sheet material
for biomedical applications and method of production |
2.05 |
3 |
| CHI00281 |
1996 |
US |
Advance Tissue Sciences Inc |
US |
5863531 |
In vitro preparation of tubular
tissue structures by stromal cell culture on a three-dimensional framework |
1.99 |
18 |
| CHI00290 |
1998 |
US |
University Of Texas |
US |
5801033 |
Gels for encapsulation of
biological materials |
1.97 |
9 |
| CHI00010 |
1992 |
CH |
Sulzer Ag |
US |
5147402 |
Implant for ingrowth of osseous
tissue |
1.93 |
40 |
| CHI00174 |
1992 |
US |
Advance Tissue Sciences Inc |
US |
5160490 |
Three-dimensional cell and
tissue culture apparatus |
1.88 |
39 |
| CHI00096 |
1997 |
IT |
Fidia Advanced Biopolymers Srl |
EP |
863776 |
A BIOLOGIC MATERIAL COMPRISING
AN EFFICIENT CULTURE OF BONE MARROW STEM CELLS PARTIALLY OR COMPLETELY
DIFFERENTIATED INTO CONNECTIVE TISSUE CELLS AND A THREE-DIMENSIONAL
BIOCOMPATIBLE AND BIODEGRADABLE MATRIX CONSISTING OF A HYALURONIC ACID
DERIVATIVE |
1.81 |
11 |
| CHI00208 |
1995 |
US |
Organogenesis Inc |
US |
5460962 |
Peracetic acid sterilization of
collagen or collagenous tissue |
1.79 |
18 |
| CHI00136 |
1985 |
US |
Mit/Mass Inst Of Technology |
US |
4505266 |
METHOD OF USING A FIBROUS
LATTICE |
1.79 |
84 |
| CHI00278 |
1996 |
US |
Advance Tissue Sciences Inc |
EP |
781116 |
THREE-DIMENSIONAL HUMAN CELL
CULTURES ON CARDIAC VALVE FRAMEWORKS AND THEIR USES |
1.77 |
16 |
| CHI00129 |
1984 |
US |
Mit/Mass Inst Of Technology |
US |
4458678 |
Cell-seeding procedures
involving fibrous lattices |
1.75 |
89 |
| CHI00215 |
1998 |
US |
Mit/Mass Inst Of Technology |
US |
5804178 |
"Implantation of
cell-matrix structure adjacent mesentery, omentum or peritoneum tissue" |
1.75 |
8 |
| CHI00245 |
1998 |
US |
Case Western Reserve University |
US |
5736396 |
Lineage-directed induction of
human mesenchymal stem cell differentiation |
1.75 |
8 |
| CHI00304 |
1998 |
US |
Focal Inc |
US |
5849035 |
Methods for intraluminal
photothermoforming |
1.75 |
8 |
| CHI00135 |
1986 |
US |
** Unassigned ** |
US |
4609551 |
PROCESS OF AND MATERIAL FOR
STIMULATING GROWTH OF CARTILAGE AND BONY TISSUE AT ANATOMICAL SITES |
1.73 |
75 |
| CHI00183 |
1993 |
US |
Regen Biologics Inc |
US |
5263984 |
Prosthetic ligaments |
1.71 |
29 |
| CHI00251 |
1996 |
US |
Advance Tissue Sciences Inc |
US |
5512475 |
Three-dimensional skin cell and
tissue culture system |
1.66 |
15 |
| CHI00181 |
1993 |
US |
Regen Biologics Inc |
US |
5258043 |
Method for making a prosthetic
intervertebral disc |
1.65 |
28 |
| CHI00221 |
1997 |
US |
Johns Hopkins University |
US |
5686091 |
Biodegradable foams for cell
transplantation |
1.65 |
10 |
| CHI00269 |
1997 |
US |
Advance Tissue Sciences Inc |
US |
5624840 |
Three-dimensional liver cell
and tissue culture system |
1.65 |
10 |
| CHI00295 |
1996 |
US |
Hmri/Clmf |
US |
5523228 |
Hydrodynamic cell culture
environment for three dimensional tissue growth |
1.55 |
14 |
| CHI00002 |
1996 |
US |
Childrens Medical Center Corp |
US |
5667778 |
Injectable bladder muscle
cells-polymer suspension for treatment of vesicoureteral reflux and
incontinence |
1.55 |
14 |
| CHI00267 |
1998 |
US |
Cytotherapeutics Inc |
US |
5795790 |
Method for controlling
proliferation and differentiation of cells encapsulated within bioartificial
organs |
1.53 |
7 |
| CHI00097 |
1998 |
IT |
Fidia Advanced Biopolymers Srl |
EP |
985029 |
HYALURONIC ACID DERIVATIVE
BASED CELL CULTURE MATRIX AND BIODEGRADABLE THREE-DIMENSIONAL MATRIX |
1.53 |
7 |
| CHI00286 |
1998 |
US |
Focal Inc |
US |
5741323 |
Polymeric article for
intraluminal photothermoforming |
1.53 |
7 |
| CHI00161 |
1992 |
US |
Nasa/Us Natl Aeronautic & Space Admin |
US |
5155034 |
Three-dimensional cell to
tissue assembly process |
1.49 |
31 |
| CHI00159 |
1990 |
US |
Regen Biologics Inc |
US |
5007934 |
Prosthetic meniscus |
1.49 |
42 |
| CHI00178 |
1993 |
US |
Mit/Mass Inst Of Technology |
EP |
610423 |
PREVASCULARIZED POLYMERIC
IMPLANTS FOR ORGAN TRANSPLANTATION |
1.47 |
25 |
| CHI00169 |
1991 |
US |
Regen Biologics Inc |
US |
5108438 |
Prosthetic intervertebral disc |
1.43 |
35 |
| CHI00127 |
1985 |
US |
Mit/Mass Inst Of Technology |
US |
4539716 |
FABRICATION OF LIVING BLOOD
VESSELS AND GLANDULAR TISSUES |
1.38 |
65 |
| CHI00132 |
1987 |
US |
Yeshiva University |
US |
4645669 |
CULTURING AND EMPLACEMENT OF
DIFFERENTIATED CELLS IN VIVO |
1.37 |
54 |
| CHI00171 |
1992 |
US |
Regen Biologics Inc |
US |
5116374 |
Prosthetic meniscus |
1.25 |
26 |
| CHI00160 |
1992 |
US |
Nasa/Us Natl Aeronautic & Space Admin |
US |
5153132 |
Three-dimensional co-culture
process |
1.25 |
26 |
| CHI00128 |
1983 |
US |
Mit/Mass Inst Of Technology |
US |
4418691 |
Method of promoting the
regeneration of tissue at a wound |
1.12 |
61 |
| CHI00146 |
1988 |
US |
Mit/Mass Inst Of Technology |
US |
4787900 |
Process for forming multilayer
bioreplaceable blood vessel prosthesis |
1.12 |
40 |
| CHI00156 |
1990 |
US |
Clemson University |
EP |
359575 |
Soft tissue implant with
micron-scale surface texture to optimize anchorage |
1.06 |
30 |
| CHI00179 |
1992 |
US |
Regen Biologics Inc |
US |
5158574 |
Prosthetic meniscus |
1.01 |
21 |
| CHI00140 |
1986 |
US |
Mit/Mass Inst Of Technology |
US |
4604346 |
SKIN-EQUIVALENT PREPARED BY THE
USE OF PUNCH BIOPSY |
0.86 |
37 |
| CHI00155 |
1990 |
US |
Mit/Mass Inst Of Technology |
US |
4902289 |
MULTILAYER BIOREPLACEABLE BLOOD
VESSEL PROSTHESIS |
0.78 |
22 |
| CHI00126 |
1982 |
US |
The University Of Medicine And Dentistry Of New Jersey |
US |
4329743 |
Bio-absorbable composite tissue
scaffold |
0.76 |
44 |
| CHI00017 |
1988 |
DE |
Mecron Medizinische Produkte Gmbh |
EP |
255797 |
Method of producing an
individually designed prosthetic appliance |
0.62 |
22 |
| CHI00125 |
1980 |
US |
** Unassigned ** |
US |
4242460 |
Cell culture device |
0.44 |
27 |
| CHI00124 |
1980 |
US |
** Unassigned ** |
US |
4242459 |
Cell culture device |
0.35 |
22 |
