Molecules in Motion: Computer Simulations Lead to a Better Understanding of Protein Structures
This graphic shows two potential inhibitors for the enzyme HIV-1 integrase. The green structure on the left side represents an inhibitor designed after initial x-ray crystallography studies of integrase structure. The purple structure on the right side shows a new, more flexible orientation for a potential inhibitor designed by the McCammon group's computer simulations.
Credit: J. Andrew McCammon, University of California, San Diego
Download the high-resolution JPG version of the image. (19 KB)
Use your mouse to right-click (Mac users may need to Ctrl-click) the link above and choose the option that will save the file or target to your computer.