Genetic Mechanisms
CONTACTS
| Name | Phone | Room | |
|---|---|---|---|
| Arcady Mushegian | amushegi@nsf.gov | (703) 292-8528 | 655 |
| Karen C. Cone | kccone@nsf.gov | (703) 292-4967 | 655 |
| Michael Weinreich | mweinrei@nsf.gov | (703) 292-7582 | 655 |
| Casonya M. Johnson | casjohns@nsf.gov | (703) 292-2968 | 655 |
| Anthony G. Garza | aggarza@nsf.gov | (703) 292-8440 | 655 |
SYNOPSIS
Apply to NSF 17-589
The cluster supports inventive studies seeking to address fundamental mechanisms involved in the evolution, organization, dynamics, and utilization of genetic information within cellular systems. Projects are encouraged that employ theoretical, computational, and experimental approaches to integrate structural, biochemical, genetic, and "omic" (genome, transcriptome, interactome, phenome, etc.) data to discover rules that help explain the relationship of genotype to molecular phenotype. Interdisciplinary research is encouraged, and when driven by compelling questions, development and use of innovative in vivo and in vitro technical and computational approaches are welcome.
Funding priority is given to proposals that employ quantitative frameworks and promise high-impact advances in the following areas:
- Chromatin- and RNA-mediated regulatory mechanisms.
- Dynamics and spatiotemporal coordination of genome replication, DNA repair, chromatin modification, transcription, and translation.
- Origin and evolution of genetic polymers, including DNA, RNA and proteins.
RELATED URLS
- What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)
- Map of Recent Awards Made Through This Program
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MCB Cluster Descriptions
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