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Systems and Synthetic Biology

Name Email Phone Room
David  A. Rockcliffe (703) 292-7123  E12473  
Elebeoba  May (703) 292-2100  E12468  
Devaki  Bhaya (703) 292-8400  offsite  
Alias  Smith (703) 292-8367  E12416  


Apply to NSF 18-585

The cluster supports proposals that make use of the tools of systems and synthetic biology to generate a comprehensive understanding of complex interactions within biological systems across different scales. Proposals using experimental and computational approaches in a synergistic fashion are a high priority. The cluster seeks proposals using tractable established or emerging model systems that focus on: regulatory and metabolic network dynamics; fundamental rules governing complex behavior; and microbial communities and their interactions.

The cluster encourages proposals that use systems and synthetic biology approaches to examine fundamental properties of biological systems in the areas of:

  • Mechanistic modeling of regulatory, signaling, and metabolic networks and the interactions among networks.
  • The origins of life, the minimal cell and emerging behaviors of complex interactions.
  • Novel experimental and computational tool development including those that facilitate the exploration and discovery of fundamental molecular scale mechanisms.
  • Molecular to system-wide scale rules of assembly and function in natural or synthetic microbial communities and symbiotic partnerships.