Systems and Synthetic Biology
|David A. Rockcliffeemail@example.com||(703) 292-7123||E12473|
|Devaki Bhayafirstname.lastname@example.org||(703) 292-7131||E12476|
|Elebeoba Mayemail@example.com||(703) 292-2100||E12468|
Apply to NSF 18-585
The cluster supports proposals that make use of the tools of systems and synthetic biology to generate a comprehensive understanding of complex interactions within biological systems across different scales. Proposals using experimental and computational approaches in a synergistic fashion are a high priority. The cluster seeks proposals using tractable established or emerging model systems that focus on: regulatory and metabolic network dynamics; fundamental rules governing complex behavior; and microbial communities and their interactions.
The cluster encourages proposals that use systems and synthetic biology approaches to examine fundamental properties of biological systems in the areas of:
- Mechanistic modeling of regulatory, signaling, and metabolic networks and the interactions among networks.
- The origins of life, the minimal cell and emerging behaviors of complex interactions.
- Novel experimental and computational tool development including those that facilitate the exploration and discovery of fundamental molecular scale mechanisms.
- Molecular to system-wide scale rules of assembly and function in natural or synthetic microbial communities and symbiotic partnerships.