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Division of Molecular and Cellular Biosciences
Division of Molecular and Cellular Biosciences: Investigator-Initiated Research Projects (MCB)
Note Guidance on Data Management Plans
BIO has posted revised Guidance on Data Management plans (updated 10/01/15). Please review before submitting a proposal to the Directorate for Biological Sciences.
Important Information for Proposers
A revised version of the NSF Proposal & Award Policies & Procedures Guide (PAPPG) (NSF 17-1), is effective for proposals submitted, or due, on or after January 30, 2017. Please be advised that, depending on the specified due date, the guidelines contained in NSF 17-1 may apply to proposals submitted in response to this funding opportunity.
Full Proposal Deadline Date
Mon Nov 20 00:00:00 EST 2017
All research proposals, including RUI and RCN proposals, will be accepted on or before this deadline.
The Division of Molecular and Cellular Biosciences (MCB) supports quantitative, mechanistic, predictive, and theory-driven fundamental research designed to promote understanding of complex living systems at the molecular, subcellular, and cellular levels. While recognizing the need for thorough and accurate descriptions of biological complexes and pathways, the priority of the Division is to support work that advances the field by capturing the predictive power of mechanistic, quantitative, and evolutionary approaches. MCB is soliciting proposals in four core clusters:
- Cellular Dynamics and Function
- Genetic Mechanisms
- Molecular Biophysics
- Systems and Synthetic Biology
MCB gives high priority to research projects that use theory, methods, and technologies from life and physical sciences, mathematics, computational sciences, and engineering to address major biological questions that elucidate the rules governing subcellular and cellular processes. Research supported by MCB uses a range of experimental and computational approaches--including in vivo, in vitro, and in silico strategies--and a broad spectrum of model and non-model organisms, including microbes and plants. Typical research supported by MCB integrates theory and experimentation. Projects are particularly welcome that address the emerging areas of: multi-scale integration; transformative methods and resources (when driven by compelling biological questions); molecular and cellular evolution; the synthesis of life-like systems; and the quantitative prediction of the phenome from genomic information. Highest funding priority is given to applications that have outstanding intellectual merit and strong broader impacts, while proposals with weaknesses in either category (or those that are perceived as likely to have an incremental impact) will not be competitive. Proposals that are motivated by relevance to human health and disease treatment are not appropriate for the Division and will be returned without review.
Revisions and Updates