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September 25, 2008

This illustration depicts how scientists use computers to understand chemical switches.

With the aid of supercomputers, researchers have been able to model the interaction of thousands of groups of molecules that behave as switches. Each set of interactions reads almost like an electrical circuit (right). They have generated a hefty catalog of possible biochemical switches. Each switch involves at least three molecules. Remarkably, some of the modeled circuits have already been identified and described by biochemists in real biological circuits (left).

Credit: Zina Deretsky, NSF


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