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March 21, 2012

First all-atom structure of an HIV virus capsid in its tubular form.

From Klaus Schulten's project about HIV infection, this image is of the first all-atom structure of an HIV virus capsid in its tubular form. Schulten and his team at the University of Illinois at Urbana-Champaign are studying the protein capsid that encases the HIV-1 genome. The process through which this capsid disassembles, releasing its genetic material, is a critical step in HIV infection. Schulten's group will simulate a cylindrical capsid consisting of 12.5 million atoms.

Credit: Courtesy of Klaus Schulten, University of Illinois at Urbana-Champaign Theoretical and Computational Biophysics Group/Beckman Institute; Angela Gronenborn and Peijun Zhang, University of Pittsburgh School of Medicine Center for HIV Protein Interactions/Department of Structural Biology.


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