Multimedia Gallery - This computer simulation predicts how two regions of a eukaryotic enzyme bind to tRNA.

Illustration from computer simulation predicting how 2 regions of a eukaryotic enzyme bind to tRNA.

November 6, 2013

This computer simulation predicts how two regions of a eukaryotic enzyme bind to tRNA.

This computer simulation predicts how two regions of a eukaryotic enzyme come together to bind to tRNA. The simulation reveals a hinge motion in the appended domain of Gln4 that has been shown to be critical to properly recognizing the tRNA molecule and (eventually) identifying new drugs.

Credit: Edward Snell, Hauptman-Woodward Medical Research Institute

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