News From the Field
Simplest Circadian Clocks Operate Via Orderly Phosphate Transfers
October 4, 2007
Researchers at Harvard University and the Howard Hughes Medical Institute have found that a simple circadian clock found in some bacteria operates by the rhythmic addition and subtraction of phosphate groups at two key locations on a single protein. This phosphate pattern is influenced by two other proteins, driving phosphorylation to oscillate according to a remarkably accurate 24-hour cycle.
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