News From the Field
Inherited Cancer Mutation is Widespread in America
April 17, 2008
A gene mutation responsible for a form of inherited colon cancer is older than formerly believed. The findings offer a better understanding of the American Founder Mutation, which in North America, causes Lynch syndrome, a hereditary cancer syndrome that increases colon-cancer risk. A 2003 study by the same investigators concluded that the mutation arrived in North America in 1727. The new study indicates that the mutation is actually about 500 years old.
Ohio State University Medical Center
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