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Protein Linked to Mental Retardation Controls Synapse Maturation, Plasticity, CSHL Team Finds


June 1, 2009

Linda Van Aelst A team of neuroscientists at Cold Spring Harbor Laboratory has demonstrated the mechanism by which a signaling protein found throughout the brain controls the maturation and strength of excitatory synapses, the tiny gaps across which the majority of neurons communicate. The discovery is important, in part, because deficits of the signaling protein in question, called oligophrenin-1, have been previously linked with X-linked mental retardation. Full Story

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Cold Spring Harbor Laboratory

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