News From the Field
Protein Linked to Mental Retardation Controls Synapse Maturation, Plasticity, CSHL Team Finds
June 1, 2009
A team of neuroscientists at Cold Spring Harbor Laboratory has demonstrated the mechanism by which a signaling protein found throughout the brain controls the maturation and strength of excitatory synapses, the tiny gaps across which the majority of neurons communicate. The discovery is important, in part, because deficits of the signaling protein in question, called oligophrenin-1, have been previously linked with X-linked mental retardation.
Cold Spring Harbor Laboratory
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