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News From the Field
Cell Surface Transporters Exploited for Cancer Drug Delivery
December 2, 2012
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According to Whitehead Institute researchers, a protein known as monocarboxylate transporter 1 (MCT1), which is highly expressed in a subset of metabolically altered cancer cells, is needed for the entry of the investigational cancer drug 3-bromopyruvate (3-BrPA) into malignant cells. This work may open a new avenue for cancer therapeutic research, as other transport molecules have already been identified on the surface of certain cancer cells.
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Whitehead Institute for Biomedical Research
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