News From the Field
Human cells' protein factory has an alternate operating manual
July 10, 2014
Working with a gene involved in HIV infection, University of Maryland (UMD) researchers discovered some human genes have an alternate set of operating instructions written into their protein-making machinery, which can quickly alter the proteins' contents, functions and ability to survive. The UMD study, published in Nature, is the first to demonstrate the phenomenon of programmed ribosomal frameshifting in a human gene. Frameshifting helps regulate the gene's immune response.
University of Maryland
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