News From the Field
Molecular switch that promotes heart cell maturation discovered
May 12, 2015
This material is available primarily for archival purposes. Telephone numbers or other contact information may be out of date; please see current contact information at media contacts.The difficulty in getting stem cells to mature into more adult-like heart cells has hindered the search for regenerative treatments for hearts damaged by disease. A molecular switch has now been discovered that appears to help embryonic heart cells switch from a glucose to fatty acid-based metabolism. They become larger, stronger, and look and act like more mature heart cells. This discovery may lead to lab methods to grow heart cells that function more like those in adult hearts.Full Story
University of Washington Health Sciences/UW Medicine
The U.S. National Science Foundation propels the nation forward by advancing fundamental research in all fields of science and engineering. NSF supports research and people by providing facilities, instruments and funding to support their ingenuity and sustain the U.S. as a global leader in research and innovation. With a fiscal year 2020 budget of $8.3 billion, NSF funds reach all 50 states through grants to nearly 2,000 colleges, universities and institutions. Each year, NSF receives more than 40,000 competitive proposals and makes about 11,000 new awards. Those awards include support for cooperative research with industry, Arctic and Antarctic research and operations, and U.S. participation in international scientific efforts.