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How head-on collisions of DNA protein machines stop replication


August 14, 2017

Head-on collisions between the protein machines that crawl along chromosomes can disrupt DNA replication and boost gene mutation rates. This may be one of the ways bacteria control their evolution by accelerating mutations in key genes when coping with new conditions. Some mutations may help bacteria survive hostile environments, resist antibiotics or fend off immune attacks. Full Story

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University of Washington Health Sciences/UW Medicine

The National Science Foundation (NSF) is an independent federal agency that supports fundamental research and education across all fields of science and engineering. In fiscal year (FY) 2017, its budget is $7.5 billion. NSF funds reach all 50 states through grants to nearly 2,000 colleges, universities and other institutions. Each year, NSF receives more than 48,000 competitive proposals for funding and makes about 12,000 new funding awards.

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