This document has been archived and replaced by NSF 05-597.
Frontiers in Integrative Biological Research (FIBR)
National Science Foundation
Preliminary Proposal Due Date(s) (required):
October 04, 2004
Required for Submission of Full Proposals (due by 5 p.m. proposer's local time)
Full Proposal Deadline(s) (due by 5 p.m. proposer's local time):
February 16, 2005
Frontiers in Integrative Biological Research (FIBR)
Synopsis of Program:
The Frontiers in Integrative Biological Research (FIBR) Program supports integrative research that addresses major questions in the biological sciences. FIBR encourages investigators to identify major under-studied or unanswered questions in biology and to use innovative approaches to address them by integrating the scientific concepts and research tools from across disciplines including biology, math and the physical sciences, engineering, social sciences and the information sciences. Proposers are encouraged to focus on the biological significance of the question, to describe the integrative approaches, and to develop a research plan that is not limited by conceptual, disciplinary, or organizational boundaries. Particularly encouraged are the inclusion of young scientists trained in an interdisciplinary environment or in non-biological disciplines, and partnerships with underrepresented minority serving and primarily undergraduate institutions and community colleges.
Cognizant Program Officer(s):
Dr. Chris Greer, FIBR Program Director, telephone: (703)292-8470, fax: (703)292-9063, email: firstname.lastname@example.org
Applicable Catalog of Federal Domestic Assistance (CFDA) Number(s):
The Directorate for Biological Sciences (BIO) of the National Science Foundation (NSF) announces the third competition for the Frontiers in Integrative Biological Research (FIBR) program. During the last decade, major breakthroughs in many areas including genomics, information technology, high throughput instrumentation, imaging and wireless technologies, sensors, and Geographic Information System (GIS) now enable novel and integrative approaches to major challenges in biology. Thus, 21st Century Biology encompasses research that is multidimensional, multidisciplinary, integrative, education-oriented and global, encompassing conceptual and experimental approaches much different from those of the previous century. While existing BIO programs support these new directions in biological research, FIBR is designed to enable larger and more integrative or interdisciplinary projects than might be possible in any single program. Through FIBR BIO intends to support groups of researchers to capitalize on synergistic interactions and to employ diverse tools to achieve an integrative understanding of a clearly defined, major biological question. Proposals that fit within the scope of another existing program at NSF should be directed to that program (see Section IX below for additional information).
NSF BIO does not provide support for bioscience research with disease related goals, including work on the etiology, diagnosis and treatment of physical and mental disease, abnormality, or malfunction in human beings or animals. Animal models of such conditions and the development and testing of drugs and other procedures for their treatment also are not eligible for support. The submission of duplicate or substantially similar proposals concurrently for review by more than one program without prior NSF approval may result in the return of the redundant proposals. Research proposals to the Biological Sciences Directorate cannot be duplicates of proposals to any other Federal agency for simultaneous consideration. The only exceptions to this rule applicable to the FIBR program are proposals from PIs who are beginning investigators (individuals who have not been a principal investigator (PI) or co-principal investigator (co-PI) on a Federally funded award with the exception of doctoral dissertation, postdoctoral fellowship or research planning grants). For proposers who qualify under this exception, the box for "Beginning Investigator" must be checked on the proposal Cover Sheet.
The FIBR program supports integrative research focused on a major question(s) in biology addressed through the creative application of a broad range of scientific concepts, strategies and research tools from both within and outside the biological sciences. FIBR projects are integrative at several conceptual levels. This includes the nature of the research paradigm (which may encompass multiple levels of organization or complexity, time and space, or range of organisms or processes), the use of combined experimental and theoretical analyses, and the application of a broad range of interdisciplinary approaches (e.g. math, physics, chemistry, social and behavioral sciences, computation and information sciences, etc.) in a single, coherent effort.
FIBR particularly encourages inclusion of young scientists trained in an interdisciplinary environment or in non-biological disciplines as co-PIs or postdoctoral research associates. The FIBR program also encourages partnerships with community colleges, baccalaureate, comprehensive, and underrepresented minority-serving institutions.
When preparing a FIBR proposal, proposers are encouraged to focus on the biological significance of the question, to describe the best integrative approaches, and to develop a plan that is not constrained by any perceived or real barriers and limitations, be they conceptual, disciplinary, organizational or budgetary. It is essential that there be an integrative conceptual model to link each element of the research plan to overall goals, and to serve as a framework for analysis of hypotheses being tested.
It is recognized that proposals that cross significant disciplinary, intellectual, or other boundaries may not fit readily within existing programs and an important goal of the FIBR program is to provide a home for such proposals. Proposals that fit within the scope of an existing program at NSF or elsewhere should be submitted directly to those programs. Examples of other programs at NSF that support large scale collaborative research can be found under Section IX below, Other Progams of Interest. Consult the NSF Guide to Programs for a complete description of NSF programs (https://www.nsf.gov/cgi-bin/getpub?gp).
The FIBR program supports the development of novel strategies, concepts and tools when these are essential elements within a broader plan to address a major and well-defined question in biology. However, projects whose primary or central focus is on new tools and strategies development are not appropriate for the FIBR program.
Large-scale projects employing broadly integrative approaches may involve international teams of investigators and NSF encourages international collaborations. FIBR program funds may be requested to support US investigators and students to work in international laboratories or foreign investigators and students to work in US laboratories. However, foreign counterparts should secure support for their efforts from their own national programs.
A two stage review process will be used for FIBR proposals. First, all proposers must submit a preliminary proposal that outlines the project as described below. Based upon review of preliminary proposals by a panel of outside experts, selected proposers will be encouraged to proceed to the second stage of review with submission of a full proposals. Those not encouraged remain eligible to submit full proposals although this is not recommended. Full proposals submitted without a corresponding preliminary proposal in the current review cycle will not be accepted.
It is anticipated that approximately $8 million will be available for new Full Proposals in FY2005, contingent upon the quality of proposals received and pending the availability of funds. The award size for research grants will be up to a total of approximately $5 million for up to five years. Funding decisions for full research proposals are anticipated by the end of July 2005, with awards expected to start in September 2005.
Letters of Intent (optional):
Preliminary Proposals (required):
The following exceptions and additions to the GPG guidelines apply to preliminary proposals submitted to this Program:
Submission of Preliminary Proposals is required for Full Proposals. Proposals that are not compliant with the guidelines may not be reviewed. It is the submitting organization's responsibility to ensure that the proposal is compliant with all applicable guidelines.
Preliminary proposals must contain the items listed below and strictly adhere to the specified page limitations. No additional information may be provided as an appendix or by links to web pages. Figures and tables must be included within the applicable page limit. All elements of the proposal, including legends and tables, must meet the formating requirements for font size, characters per inch, margins, etc. as specified in the Grant Proposal Guide.
Based on evaluation by a panel of outside experts, the FIBR Working Group expects to encourage approximately 20 to 25 Principal Investigators (PIs) to submit full proposals.
By December 17, 2004 the program will e-mail PIs whose preliminary proposals are encouraged for full proposal submission.
Preliminary proposals should provide a brief overview of the project and should include sufficient information to allow assessment of the main ideas and approaches. Preliminary proposals must include the following items:
Full Proposal Instructions:
Proposals submitted in response to this program announcement/solicitation should be prepared and submitted in accordance with the general guidelines contained in the NSF Grant Proposal Guide (GPG). The complete text of the GPG is available electronically on the NSF Website at: https://www.nsf.gov/cgi-bin/getpub?gpg. Paper copies of the GPG may be obtained from the NSF Publications Clearinghouse, telephone (703) 292-7827 or by e-mail from email@example.com.
The following exceptions and additions to the GPG guidelines apply to full proposals submitted to this Program:
Full proposals will be accepted only from PIs who have submitted Preliminary proposals in the current review cycle . Submission of full proposals by PIs whose preliminary proposals received a review recommendation of 'not encouraged' is strongly discouraged.
- Results from Prior Research: Describe prior research of PI or co-PIs funded by NSF that is directly relevant to the proposed project.
- Proposed Research: Describe the vision and goals of the proposed research, the major question(s) in biology to be addressed, approaches to attain the goals, any new techniques or tools expected to be developed, expected outcomes, and how the proposed project will advance the frontiers of biology. Articulate unifying and integrative aspects of the proposed research as well as the innovative ideas of the research.
- Education and Training Plan: Describe how the proposed research will be integrated with educational activities and how these activities promote diversity as an integral component. Indicate how students trained in this research will be better able to handle emerging research problems in biological sciences. These plans should take advantage of unique aspects of the proposed research and the research environment, with particular emphasis on increasing participation of underrepresented groups or students and faculty from under-served institutions or both.
- List of key personnel involved (maximum 3 pages), with description of what each person uniquely brings to the project and how they are integrated to produce positive synergies;
- Provide a detailed management plan (maximum 3 pages) including means of communication and data tracking/management within the group, management of intellectual property resulting from the project, and timeline of activities;
- Means of sharing the outcome of the research with the rest of the scientific community, eg. publications, web sites, data bases, genome, EST, cDNA or other sequences, microarray data, etc. (maximum 2 pages). The description should be specific and describe what, how, and when the community would have access to the outcome of the project. This is particularly important for the projects that will produce tangible research tools and resources;
- A list, in a single alphabetized table, with the full names of all people with conflicts of interest for all senior personnel (PI and Co-PI's) and any named personnel whose salary is requested in the project budget. Conflicts to be identified are (1) PhD thesis advisors or advisees, (2) collaborators or co-authors, including postdocs, for the past 48 months, and (3) any other individuals or institutions with which the investigator has financial ties (please specify type).
Proposers are reminded to identify the program announcement/solicitation number (04-596) in the program announcement/solicitation block on the proposal Cover Sheet. Compliance with this requirement is critical to determining the relevant proposal processing guidelines. Failure to submit this information may delay processing.
Cost sharing is not required in proposals submitted under this Program Solicitation.
Proposals must be submitted by the following date(s):
Preliminary Proposals (required):
Full Proposal Deadline(s) (due by 5 p.m. proposer's local time):
Proposers are required to prepare and submit all proposals for this announcement/solicitation through the FastLane system. Detailed instructions for proposal preparation and submission via FastLane are available at: https://www.fastlane.nsf.gov/a1/newstan.htm. For FastLane user support, call the FastLane Help Desk at 1-800-673-6188 or e-mail firstname.lastname@example.org. The FastLane Help Desk answers general technical questions related to the use of the FastLane system. Specific questions related to this program announcement/solicitation should be referred to the NSF program staff contact(s) listed in Section VIII of this announcement/solicitation.
Submission of Electronically Signed Cover Sheets. The Authorized Organizational Representative (AOR) must electronically sign the proposal Cover Sheet to submit the required proposal certifications (see Chapter II, Section C of the Grant Proposal Guide for a listing of the certifications). The AOR must provide the required electronic certifications within five working days following the electronic submission of the proposal. Proposers are no longer required to provide a paper copy of the signed Proposal Cover Sheet to NSF. Further instructions regarding this process are available on the FastLane Website at: http://www.fastlane.nsf.gov
Reviews of proposals submitted to NSF are solicited from peers with expertise in the substantive area of the proposed research or education project. These reviewers are selected by Program Officers charged with the oversight of the review process. NSF invites the proposer to suggest, at the time of submission, the names of appropriate or inappropriate reviewers. Care is taken to ensure that reviewers have no conflicts with the proposer. Special efforts are made to recruit reviewers from non-academic institutions, minority-serving institutions, or adjacent disciplines to that principally addressed in the proposal.
The National Science Board approved revised criteria for evaluating proposals at its meeting on March 28, 1997 (NSB 97-72). All NSF proposals are evaluated through use of the two merit review criteria. In some instances, however, NSF will employ additional criteria as required to highlight the specific objectives of certain programs and activities.
On July 8, 2002, the NSF Director issued Important Notice 127, Implementation of new Grant Proposal Guide Requirements Related to the Broader Impacts Criterion. This Important Notice reinforces the importance of addressing both criteria in the preparation and review of all proposals submitted to NSF. NSF continues to strengthen its internal processes to ensure that both of the merit review criteria are addressed when making funding decisions.
In an effort to increase compliance with these requirements, the January 2002 issuance of the GPG incorporated revised proposal preparation guidelines relating to the development of the Project Summary and Project Description. Chapter II of the GPG specifies that Principal Investigators (PIs) must address both merit review criteria in separate statements within the one-page Project Summary. This chapter also reiterates that broader impacts resulting from the proposed project must be addressed in the Project Description and described as an integral part of the narrative.
Effective October 1, 2002, NSF will return without review proposals that do not separately address both merit review criteria within the Project Summary. It is believed that these changes to NSF proposal preparation and processing guidelines will more clearly articulate the importance of broader impacts to NSF-funded projects.
The two National Science Board approved merit review criteria are listed below (see the Grant Proposal Guide Chapter III.A for further information). The criteria include considerations that help define them. These considerations are suggestions and not all will apply to any given proposal. While proposers must address both merit review criteria, reviewers will be asked to address only those considerations that are relevant to the proposal being considered and for which he/she is qualified to make judgments.
NSF staff will give careful consideration to the following in making funding decisions:
All proposals are carefully reviewed by at least three other persons outside NSF who are experts in the particular field represented by the proposal. Proposals submitted in response to this announcement/solicitation will be reviewed by Ad Hoc and/or panel review.
Reviewers will be asked to formulate a recommendation to either support or decline each proposal. The Program Officer assigned to manage the proposal's review will consider the advice of reviewers and will formulate a recommendation.
A summary rating and accompanying narrative will be completed and submitted by each reviewer. In all cases, reviews are treated as confidential documents. Verbatim copies of reviews, excluding the names of the reviewers, are sent to the Principal Investigator/Project Director by the Program Director. In addition, the proposer will receive an explanation of the decision to award or decline funding.
NSF is striving to be able to tell proposers whether their proposals have been declined or recommended for funding within six months. The time interval begins on the closing date of an announcement/solicitation, or the date of proposal receipt, whichever is later. The interval ends when the Division Director accepts the Program Officer's recommendation.
In all cases, after programmatic approval has been obtained, the proposals recommended for funding will be forwarded to the Division of Grants and Agreements for review of business, financial, and policy implications and the processing and issuance of a grant or other agreement. Proposers are cautioned that only a Grants and Agreements Officer may make commitments, obligations or awards on behalf of NSF or authorize the expenditure of funds. No commitment on the part of NSF should be inferred from technical or budgetary discussions with a NSF Program Officer. A Principal Investigator or organization that makes financial or personnel commitments in the absence of a grant or cooperative agreement signed by the NSF Grants and Agreements Officer does so at their own risk.
Notification of the award is made to the submitting organization by a Grants Officer in the Division of Grants and Agreements. Organizations whose proposals are declined will be advised as promptly as possible by the cognizant NSF Program Division administering the program. Verbatim copies of reviews, not including the identity of the reviewer, will be provided automatically to the Principal Investigator. (See section VI.A. for additional information on the review process.)
An NSF award consists of: (1) the award letter, which includes any special provisions applicable to the award and any numbered amendments thereto; (2) the budget, which indicates the amounts, by categories of expense, on which NSF has based its support (or otherwise communicates any specific approvals or disapprovals of proposed expenditures); (3) the proposal referenced in the award letter; (4) the applicable award conditions, such as Grant General Conditions (NSF-GC-1); * or Federal Demonstration Partnership (FDP) Terms and Conditions * and (5) any announcement or other NSF issuance that may be incorporated by reference in the award letter. Cooperative agreement awards also are administered in accordance with NSF Cooperative Agreement Terms and Conditions (CA-1). Electronic mail notification is the preferred way to transmit NSF awards to organizations that have electronic mail capabilities and have requested such notification from the Division of Grants and Agreements.
*These documents may be accessed electronically on NSF's Website at https://www.nsf.gov/home/grants/grants_gac.htm. Paper copies may be obtained from the NSF Publications Clearinghouse, telephone (703) 292-7827 or by e-mail from email@example.com.
More comprehensive information on NSF Award Conditions is contained in the NSF Grant Policy Manual (GPM) Chapter II, available electronically on the NSF Website at https://www.nsf.gov/cgi-bin/getpub?gpm. The GPM is also for sale through the Superintendent of Documents, Government Printing Office (GPO), Washington, DC 20402. The telephone number at GPO for subscription information is (202) 512-1800. The GPM may be ordered through the GPO Website at http://www.gpo.gov.
For all multi-year grants (including both standard and continuing grants), the PI must submit an annual project report to the cognizant Program Officer at least 90 days before the end of the current budget period.
Within 90 days after the expiration of an award, the PI also is required to submit a final project report. Failure to provide final technical reports delays NSF review and processing of pending proposals for the PI and all Co-PIs. PIs should examine the formats of the required reports in advance to assure availability of required data.
PIs are required to use NSF's electronic project reporting system, available through FastLane, for preparation and submission of annual and final project reports. This system permits electronic submission and updating of project reports, including information on project participants (individual and organizational), activities and findings, publications, and other specific products and contributions. PIs will not be required to re-enter information previously provided, either with a proposal or in earlier updates using the electronic system.
General inquiries regarding this program should be made to:
Dr. Chris Greer, FIBR Program Director, telephone: (703)292-8470, fax: (703)292-9063, email: firstname.lastname@example.org
For questions related to the use of FastLane, contact:
The FastLane Help Desk, telephone: 800-673-6188, email: email@example.com
The Divisional FastLane Contact answers policy/program announcement questions, telephone: 703 292-8470, email: firstname.lastname@example.org
The NSF Guide to Programs is a compilation of funding for research and education in science, mathematics, and engineering. The NSF Guide to Programs is available electronically at https://www.nsf.gov/cgi-bin/getpub?gp. General descriptions of NSF programs, research areas, and eligibility information for proposal submission are provided in each chapter.
Many NSF programs offer announcements or solicitations concerning specific proposal requirements. To obtain additional information about these requirements, contact the appropriate NSF program offices. Any changes in NSF's fiscal year programs occurring after press time for the Guide to Programs will be announced in the NSF E-Bulletin, which is updated daily on the NSF Website at https://www.nsf.gov/home/ebulletin, and in individual program announcements/solicitations. Subscribers can also sign up for NSF's Custom News Service (https://www.nsf.gov/home/cns/start.htm) to be notified of new funding opportunities that become available.
Examples of other programs at NSF that support large scale, collaborative research include the following:
Consult the NSF Guide to Programs (https://www.nsf.gov/cgi-bin/getpub?gp) for information about these and other activities.
The National Science Foundation (NSF) funds research and education in most fields of science and engineering. Awardees are wholly responsible for conducting their project activities and preparing the results for publication. Thus, the Foundation does not assume responsibility for such findings or their interpretation.
NSF welcomes proposals from all qualified scientists, engineers and educators. The Foundation strongly encourages women, minorities and persons with disabilities to compete fully in its programs. In accordance with Federal statutes, regulations and NSF policies, no person on grounds of race, color, age, sex, national origin or disability shall be excluded from participation in, be denied the benefits of, or be subjected to discrimination under any program or activity receiving financial assistance from NSF, although some programs may have special requirements that limit eligibility.
Facilitation Awards for Scientists and Engineers with Disabilities (FASED) provide funding for special assistance or equipment to enable persons with disabilities (investigators and other staff, including student research assistants) to work on NSF-supported projects. See the GPG Chapter II, Section D.2 for instructions regarding preparation of these types of proposals.
The National Science Foundation promotes and advances scientific progress in the United States by competitively awarding grants and cooperative agreements for research and education in the sciences, mathematics, and engineering.
To get the latest information about program deadlines, to download copies of NSF publications, and to access abstracts of awards, visit the NSF Website at https://www.nsf.gov
The information requested on proposal forms and project reports is solicited under the authority of the National Science Foundation Act of 1950, as amended. The information on proposal forms will be used in connection with the selection of qualified proposals; project reports submitted by awardees will be used for program evaluation and reporting within the Executive Branch and to Congress. The information requested may be disclosed to qualified reviewers and staff assistants as part of the proposal review process; to applicant institutions/grantees to provide or obtain data regarding the proposal review process, award decisions, or the administration of awards; to government contractors, experts, volunteers and researchers and educators as necessary to complete assigned work; to other government agencies needing information as part of the review process or in order to coordinate programs; and to another Federal agency, court or party in a court or Federal administrative proceeding if the government is a party. Information about Principal Investigators may be added to the Reviewer file and used to select potential candidates to serve as peer reviewers or advisory committee members. See Systems of Records, NSF-50, "Principal Investigator/Proposal File and Associated Records," 63 Federal Register 267 (January 5, 1998), and NSF-51, "Reviewer/Proposal File and Associated Records," 63 Federal Register 268 (January 5, 1998). Submission of the information is voluntary. Failure to provide full and complete information, however, may reduce the possibility of receiving an award.
An agency may not conduct or sponsor, and a person is not required to respond to an information collection unless it displays a valid OMB control number. The OMB control number for this collection is 3145-0058. Public reporting burden for this collection of information is estimated to average 120 hours per response, including the time for reviewing instructions. Send comments regarding this burden estimate and any other aspect of this collection of information, including suggestions for reducing this burden, to: Suzanne Plimpton, Reports Clearance Officer, Division of Administrative Services, National Science Foundation, Arlington, VA 22230.
OMB control number: 3145-0058.
The National Science Foundation, 4201 Wilson Boulevard, Arlington, Virginia 22230, USA