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Press Release 07-100
New, More Direct Pathways from Outside of Cells to Cell Nuclei Discovered

Material outside of a cell can move into cell nucleus more easily than previously believed

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Material is transported from outside of the cell to cell nucleus.

1. Phagocytosis and endocytosis: the cell membrane pinches together, and thereby forms an intracellular membrane-bound compartment, called a phagosome or endosome, that contains extracellular material.

2. The phagosome travels from the cell membrane to the nucleus.

3. The phagosome is engulfed by the nucleus, and then releases its contents into the nucleus.

Credit: Nicolle Rager Fuller, National Science Foundation

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