Macromolecular, Supramolecular and Nanochemistry

The Macromolecular, Supramolecular and Nanochemistry (MSN) Program focuses on basic research that addresses fundamental questions and advances knowledge regarding the chemistry of macromolecular, supramolecular, and nanoscopic structures. Research of interest to this program will explore novel chemistry concepts including, but not limited to: synthesis of macromolecular, supramolecular and nanoscopic structures; surface functionalization methodologies; surface monolayer chemistry; and template-directed synthesis; inter- and intra-molecular interactions that give rise to macromolecular, supramolecular or nanoparticulate self-assembly into discrete structures; and chemical dynamics that are responsible for spatial organization in discrete organic, inorganic, or hybrid systems (excluding extended solids).  Also included are advanced experimental or computational methods to delineate or to predict the chemical structure, unique chemical and physicochemical properties, and chemical reactivity that result from macromolecular, supramolecular, and nanoscopic structures, including systems that exhibit quantum confinement and other non-classical effects. Projects which demonstrate synergy between experiment and theory are of special interest.

Submissions that advance MSN chemistry knowledge important for addressing national needs in sustainability are strongly encouraged.  Examples include, but are not limited to: transformative approaches to efficient and inexpensive synthesis using renewable feedstocks or earth abundant elements; and innovative research that enhances the understanding of efficient use and recycling of critical elements or the conversion of energy from renewable sources.

Proposals for which the primary focus is on single molecules, extended solids (including metal organic frameworks), materials research, fate of nanoparticles in the environment, device properties, engineering, biological properties (including toxicity), drug delivery, or selection or genetic engineering of enzymes are not of interest in the MSN Program.  Investigators interested in these areas are encouraged to approach other, more closely aligned programs such as those in the Divisions of Materials Research (DMR), Physics (PHY), and Chemical, Bioengineering, Environmental, and Transport Systems (CBET).