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Chemistry of Life Processes  (CLP)


Name Email Phone Room
David  A. Rockcliffe drockcli@nsf.gov (703) 292-7123  1055 S  
Carl  Carrano ccarrano@nsf.gov (703) 292-4336  1055 S  

Administrative Program Support: Marla Stewart, mastewar@nsf.gov or
(703) 292-8735


Apply to PD 09-6883 as follows:

For full proposals submitted via FastLane: standard Grant Proposal Guide proposal preparation guidelines apply.
For full proposals submitted via Grants.gov: the NSF Grants.gov Application Guide; A Guide for the Preparation and Submission of NSF Applications via Grants.gov Guidelines applies. (Note: The NSF Grants.gov Application Guide is available on the Grants.gov website and on the NSF website at: http://www.nsf.gov/publications/pub_summ.jsp?ods_key=grantsgovguide)

Important Information for Proposers

A revised version of the NSF Proposal & Award Policies & Procedures Guide (PAPPG) (NSF 16-1), is effective for proposals submitted, or due, on or after January 25, 2016. Please be advised that, depending on the specified due date, the guidelines contained in NSF 16-1 may apply to proposals submitted in response to this funding opportunity.


Full Proposal Window:  October 1, 2016 - October 31, 2016

October 1 - October 31, Annually Thereafter

Note that if the last day of a submission window falls on a weekend or official Federal government holiday, the deadline is always the following business day, at 5 pm local time.


"Note: for a proposal with significant emphasis on understanding of the role of the chemistry of nitrogen, phosphorous, and water in the nexus of food, energy and water systems, consider making proposal submissions to this program with the Proposal Title as 'INFEWS: N/P/H20: Name of  Your Proposal.' For more information, see the FY 2015 DCL on Innovations at the Nexus of Food, Energy and Water Systems (INFEWS) Funding Opportunity on Nitrogen, Phosphorus, and Water (http://www.nsf.gov/publications/pub_summ.jsp?ods_key=nsf15108), a new NSF Emphasis Area." 

"Note:  For proposals with significant emphasis on sustainable chemistry, consider making proposal submissions to this program with the Proposal Title as:  ‘SusChEM: Name of Your Proposal'.  For more information, see the DCL on SusChEM (http://www.nsf.gov/pubs/2013/nsf13013/nsf13013.pdf), a new NSF Emphasis Area."   

The Chemistry of Life Processes (CLP) Program supports fundamental studies of biomolecules or biological systems at the interface of chemistry and biology. The primary contributions and innovations of the proposed research focus on the chemical aspects of the project. The Program supports studies that investigate how molecular structure, dynamics and interactions, as well as reaction thermodynamics and mechanisms are integrated with the chemistry performed by, or intrinsic to, the biological systems.

Research projects typically employ experimental, computational or integrated approaches to investigate biological systems such as, but not limited to, proteins, nucleic acids, carbohydrates or lipids.  The scope of the research and the methods used to conduct the research are intrinsically interdisciplinary. Projects that use or reveal novel chemistries, in advancing the understanding of biological function, are particularly welcome.  Research projects on chemical methods development applied to biological problems are acceptable.  Proposals in the following areas are encouraged:

  • The development of bio-orthogonal chemistry for probing cellular function
  • The  quantitative understanding of thermodynamics as applied to a cellular system
  • Biomolecular design, synthesis and engineering aimed at understanding biological function
  • The use of theory, computation, modeling and/or simulation as applied to the chemical aspects of biological systems

Note: The CLP Program is interested in understanding function rather than malfunction or dysfunction.  Projects with disease-related goals are not appropriate for review in the CLP program. 


Disciplinary Research Activities

What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)

Map of Recent Awards Made Through This Program



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