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February 17, 2010

"Branching Morphogenesis" illustrates the forces lung cells exert as they form capillaries

"Branching Morphogenesis" aims to reveal--through abstraction--the unseen beauty and dynamic relationships that exist between endothelial cells and their surrounding extracellular microenvironment. Movies of networking endothelial cells cultured on a 3-D matrix were analyzed to generate computational tools that simulate this process. Next, large-scale templates from simulations were overlaid with more than 75,000 inter-connected zipties.

Credit: Peter Lloyd Jones, Andrew Lucia, and Jenny E. Sabin, University of Pennsylvania's Sabin + Jones Lab Studio


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