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NSF's implementation of the revised 2 CFR

NSF Financial Assistance awards (grants and cooperative agreements) made on or after October 1, 2024, will be subject to the applicable set of award conditions, dated October 1, 2024, available on the NSF website. These terms and conditions are consistent with the revised guidance specified in the OMB Guidance for Federal Financial Assistance published in the Federal Register on April 22, 2024.

Important information for proposers

All proposals must be submitted in accordance with the requirements specified in this funding opportunity and in the NSF Proposal & Award Policies & Procedures Guide (PAPPG) that is in effect for the relevant due date to which the proposal is being submitted. It is the responsibility of the proposer to ensure that the proposal meets these requirements. Submitting a proposal prior to a specified deadline does not negate this requirement.

Updates to NSF Research Security Policies

On July 10, 2025, NSF issued an Important Notice providing updates to the agency's research security policies, including a research security training requirement, Malign Foreign Talent Recruitment Program annual certification requirement, prohibition on Confucius institutes and an updated FFDR reporting and submission timeline.

Supports interdisciplinary research aimed at mechanistic understanding of the structure, function and evolution of cellular and subcellular systems across the tree of life.

Supports interdisciplinary research aimed at mechanistic understanding of the structure, function and evolution of cellular and subcellular systems across the tree of life.

Synopsis

NSF BIO supports fundamental cell biological research.  We seek proposals that use multidisciplinary approaches to provide insights into the fundamental biology of cells from all domains of life, including understudied cell types and cells from understudied species.  Proposals that are primarily descriptive are given lower priority.

We particularly encourage proposals in the following areas:

  • Predictive understanding of cell behavior through integration of experimentation with computational modeling;
  • Evolutionary approaches to understanding cellular functions, structure, and behavior;
  • Integration of cellular structure and function with emergent properties across broad spatiotemporal scales, and;
  • Development or adaption of innovative tools or technologies to enable novel approaches to investigate cell function.

Program contacts

Name Email Phone Organization
Matthew J. Buechner
mbuechne@nsf.gov (703) 292-4675 BIO/MCB
Pablo I. Artigas
partigas@nsf.gov (703) 292-4251 BIO/MCB
Clifford Weil
cweil@nsf.gov (703) 292-4668 BIO/MCB

Awards made through this program

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