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Division of Molecular and Cellular Biosciences

Molecular Biophysics

Name Email Phone Room
Wilson  Francisco (703) 292-7856  E12481  
Engin  Serpersu (703) 292-7124  E12471  
Jaroslaw  Majewski (703) 292-7278  E12463  
Manju  Hingorani (703) 292-7323  E 12476  
Marcia  Newcomer (703) 292-4778  E12416  


Apply to NSF 17-589

The cluster supports research into the structure and dynamics of biomolecules. Research with a goal to establish the fundamental principles that underlie biomolecular interactions, regulation of biological function at the atomic, near-atomic, and molecular levels, or to use these principles to design new functions is of interest to the cluster. Studies that utilize robust experimental and computational approaches in a synergistic fashion receive the highest priority. The cluster encourages studies under conditions that mimic the native physiological environment, and seeks research at the interface of the biological sciences with the physical, chemical, mathematical and engineering sciences. Proposals involving mechanistic biochemistry or those that involve the study of systems from which broad biological principles cannot be derived will be given lower priority.

Proposals in the following areas are particularly encouraged:

  • Large scale computations comprising of millions of atoms that incorporate experimental constraints obtained using a variety of techniques ranging from NMR to high-resolution electron microscopy.
  • Methodological developments that provide insight into molecular dynamics on multiple timescales with a goal towards understanding their role in molecular recognition and function.
  • Determination of the structure and interactions of very large assemblies (e.g., ribosomes, photosystems) at high resolution.