This program has been archived.
Division of Chemical, Bioengineering, Environmental and Transport Systems
Advanced Biomanufacturing of Therapeutic Cells (ABTC)
|Carol Lucasfirstname.lastname@example.org||(703) 292-4608|
|Rajakkannu . Mutharasanemail@example.com||(703) 292-4608|
Important Information for Proposers
A revised version of the NSF Proposal & Award Policies & Procedures Guide (PAPPG) (NSF 19-1), is effective for proposals submitted, or due, on or after February 25, 2019. Please be advised that, depending on the specified due date, the guidelines contained in NSF 19-1 may apply to proposals submitted in response to this funding opportunity.
In recent years, somatic cells as therapeutic agents have provided new treatment approaches for a number of pathological conditions that were deemed untreatable, or difficult to treat. Several successful cell therapies using T cells have been demonstrated for cancer and autoimmune diseases, while stem cell therapies have given relief for heart disease and stroke. Hundreds of clinical trials are ongoing to examine efficacy of cell therapies for a variety of other diseases including diabetes, Alzheimer’s, Parkinson’s, and Crohn’s disease. Production of therapeutic cells is currently expensive and, therefore, cost prohibitive for the large number of people who might benefit from these treatments. The overarching goal of this Advanced Biomanufacturing of Therapeutic Cells (ABTC) solicitation is to catalyze well-integrated interdisciplinary research to understand, design, and control cell manufacturing systems and processes that will enable reproducible, cost-effective, and high-quality production of cells with predictable performance for the identified therapeutic function.