A map of the fruit fly brain

Core Biological Sciences Research

The U.S. National Science Foundation Directorate for Biological Sciences (NSF BIO) supports foundational research across all areas of biology.

Funding opportunities support projects that expand the frontiers of knowledge in biological sciences and technology. NSF BIO supports research that advances fundamental understanding of the dynamics, functions, and interactions of biological systems at all scales of organization, ranging from molecules to organisms to ecosystems.

Key research themes

Colorful, stylized illustration of the proteins and other structures cluttering the interior of an E. coli cell.

Foundations of life

Understanding natural or synthetic molecules, cells, and physiology that build living things.

Read more about the Foundations of Life program.

A green stick insect sitting on green leaves.

Living systems

Understanding how species evolve, interact and shape Earth's biodiverse ecosystems.

Read more about the Living Systems program.

A researcher in a lab lit with blue light looking into tanks of water containing aquatic plants and fish.

Bioinnovation and infrastructure

Investigating the functional genomic complexity of life and developing the tools, data and technologies to drive biological discovery.

Read more about the Bioinnovation and Infrastructure program.

Stay connected

Contact BIO
Reach out to program directors in the three BIO thematic areas: Foundations of Life (bio-fl@nsf.gov), Living Systems (bio-ls@nsf.gov), Bioinnovation and Infrastructure (bio-bi@nsf.gov).

Find funding
Search for programs and funding opportunities.

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Attend virtual office hours webinars
Hear from BIO program directors about funding opportunities and proposal submission.

Search for BIO awards
See examples of current and past projects.